catalog number :
MBS076573
products type :
ELISA Kit
products full name :
Mouse Dermcidin ELISA Kit
products short name :
[Dermcidin]
other names :
[dermcidin isoform 1 preproprotein; Dermcidin; dermcidin; preproteolysin; survival promoting peptide; proteolysis inducing factor; diffusible survival/evasion peptide; dermcidin; Preproteolysin]
products gene name :
[DCD]
other gene names :
[DCD; DCD; PIF; AIDD; DSEP; HCAP; DCD-1; AIDD; DSEP]
uniprot entry name :
DCD_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625umol/L-20umol/L. Sensitivity: 0.1umol/L.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of DBIL (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_444513.1
ncbi gb acc num :
NM_053283.3
ncbi mol weight :
11,284 Da
ncbi summary :
This gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
uniprot summary :
DCD: DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.4.-.-; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 12q13.1. Cellular Component: extracellular region. Molecular Function: peptidase activity. Biological Process: killing of cells of another organism; defense response to bacterium; proteolysis; defense response to fungus
size4 :
10x96-Strip-Wells