catalog number :
MBS067270
products type :
ELISA Kit
products full name :
Rat Lipase, Monoacylglycerol ELISA Kit
products short name :
[Lipase, Monoacylglycerol]
other names :
[monoglyceride lipase isoform 3; Monoglyceride lipase; monoglyceride lipase; monoacylglycerol lipase; lysophospholipase homolog; monoglyceride lipase; HU-K5; Lysophospholipase homolog; Lysophospholipase-like; Monoacylglycerol lipase]
products gene name :
[MGL]
other gene names :
[MGLL; MGLL; MGL; HUK5; MAGL; HU-K5; MGL; MAGL]
uniprot entry name :
MGLL_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Body Fluids, Tissue Homogenates, Secretions Or Feces Samples. Assay Type: Quantitative Sandwich. Detection Range: 31.2 ng/ml-1000 ng/ml. Sensitivity: 5.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MFAP2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001243514.1
ncbi gb acc num :
NM_001256585.1
ncbi mol weight :
33,261 Da
ncbi pathways :
Acyl Chain Remodeling Of DAG And TAG Pathway (645315); Acylglycerol Degradation Pathway (413388); Acylglycerol Degradation Pathway (468272); Arachidonate Production From DAG Pathway (161024); Effects Of PIP2 Hydrolysis Pathway (106044); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); Glycerolipid Metabolism Pathway (82986); Glycerolipid Metabolism Pathway (361)
ncbi summary :
This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
uniprot summary :
MGLL: Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. Belongs to the AB hydrolase superfamily. Monoacylglycerol lipase family. Protein type: Lipid Metabolism - glycerolipid; Phospholipase; EC 3.1.1.23. Chromosomal Location of Human Ortholog: 3q21.3. Cellular Component: nucleoplasm; endoplasmic reticulum membrane; extrinsic to membrane; plasma membrane; synapse; cytosol. Molecular Function: protein homodimerization activity; acylglycerol lipase activity; lipid binding; lysophospholipase activity. Biological Process: platelet activation; glycerophospholipid biosynthetic process; regulation of signal transduction; regulation of axon extension; phospholipid metabolic process; regulation of inflammatory response; triacylglycerol catabolic process; arachidonic acid metabolic process; lipid metabolic process; regulation of sensory perception of pain; blood coagulation; inflammatory response; fatty acid biosynthetic process; acylglycerol catabolic process
size4 :
10x96-Strip-Wells