catalog number :
MBS065625
products type :
ELISA Kit
products full name :
Mouse Uroplakin 3A ELISA Kit
products short name :
[Uroplakin 3A]
other names :
[uroplakin-3a isoform 2; Uroplakin-3a; uroplakin-3a; uroplakin 3; uroplakin III; uroplakin 3A; Uroplakin III]
products gene name :
[UPK3A]
other gene names :
[UPK3A; UPK3A; UP3A; UPK3; UPIII; UPIIIA; UPK3; UP3a; UPIII]
uniprot entry name :
UPK3A_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of UPK3A (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001161046.1
ncbi gb acc num :
NM_001167574.1
ncbi mol weight :
30,670 Da
ncbi summary :
This gene encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Mutations in this gene may be associated with renal adysplasia. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009]
uniprot summary :
UPK3A: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence. Defects in UPK3A are a cause of renal adysplasia (RADYS); also known as renal agenesis or renal aplasia. Renal agenesis refers to the absence of one (unilateral) or both (bilateral) kidneys at birth. Bilateral renal agenesis belongs to a group of perinatally lethal renal diseases, including severe bilateral renal dysplasia, unilateral renal agenesis with contralateral dysplasia and severe obstructive uropathy. Belongs to the uroplakin-3 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 22q13.31. Cellular Component: endoplasmic reticulum membrane; apical plasma membrane; integral to membrane. Biological Process: urinary bladder development; epithelial cell differentiation; water transport; urea transport; cell morphogenesis; sodium ion homeostasis; kidney development; potassium ion homeostasis. Disease: Renal Hypodysplasia/aplasia 1
size4 :
10x96-Strip-Wells