Bovine C-Type Lectin Domain Family 3, Member B ELISA Kit | MyBioSource MBS065456 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Bovine C-Type Lectin Domain Family 3, Member B ELISA Kit

catalog :

MBS065456

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS065456

products type :

ELISA Kit

products full name :

Bovine C-Type Lectin Domain Family 3, Member B ELISA Kit

products short name :

[C-Type Lectin Domain Family 3, Member B]

other names :

[C-type lectin domain family 7 member A isoform b; C-type lectin domain family 7 member A; C-type lectin domain family 7 member A; dectin-1; beta-glucan receptor; lectin-like receptor 1; DC-associated C-type lectin 1; C-type lectin superfamily member 12; dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7, member A; Beta-glucan receptor; C-type lectin superfamily member 12; Dendritic cell-associated C-type lectin 1]

products gene name :

[CLEC3B]

other gene names :

[CLEC7A; CLEC7A; BGR; CANDF4; DECTIN1; CLECSF12; BGR; CLECSF12; DECTIN1; DC-associated C-type lectin 1; Dectin-1]

uniprot entry name :

CLC7A_HUMAN

reactivity :

Bovine

sequence length :

201

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Bovine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.625 ug/ml - 20 ug/ml. Sensitivity: 0.1 ug/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CLEC3B (hereafter termed "analyte") in undiluted original Bovine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

13384604

ncbi acc num :

NP_072092.2

ncbi gb acc num :

NM_022570.4

uniprot acc num :

Q9BXN2

ncbi mol weight :

27,627 Da

ncbi pathways :

Phagosome Pathway (153910); Phagosome Pathway (153859); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)

ncbi summary :

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]

uniprot summary :

dectin-1: Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation. Up-regulated during differentiation from monocytes into dendritic cells. Isoform 5 interacts with RANBP9. 8 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 12p13.2. Cellular Component: cytoplasm; integral to membrane; plasma membrane. Molecular Function: metal ion binding; MHC protein binding; carbohydrate binding; pattern recognition receptor activity. Biological Process: T cell activation; innate immune response; carbohydrate mediated signaling; cell recognition; phagocytosis, recognition; pattern recognition receptor signaling pathway; defense response to protozoan; inflammatory response. Disease: Candidiasis, Familial, 4; Aspergillosis, Susceptibility To

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage