Canine Lysosomal Associated Membrane Protein 2 ELISA Kit | MyBioSource MBS065061 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Canine Lysosomal Associated Membrane Protein 2 ELISA Kit

catalog :

MBS065061

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS065061

products type :

ELISA Kit

products full name :

Canine Lysosomal Associated Membrane Protein 2 ELISA Kit

products short name :

[Lysosomal Associated Membrane Protein 2]

other names :

[Lysosome membrane protein 2; Lysosome membrane protein 2; lysosome membrane protein 2; LIMP II; CD36 antigen-like 2; lysosome membrane protein II; 85 kDa lysosomal membrane sialoglycoprotein; 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II); scavenger receptor class B, member 2; 85 kDa lysosomal membrane sialoglycoprotein; LGP85; CD36 antigen-like 2; Lysosome membrane protein II; LIMP II; Scavenger receptor class B member 2]

products gene name :

[LAMP2]

other gene names :

[SCARB2; SCARB2; AMRF; EPM4; LGP85; CD36L2; HLGP85; LIMP-2; LIMPII; SR-BII; CD36L2; LIMP2; LIMPII; LGP85; LIMP II]

uniprot entry name :

SCRB2_HUMAN

reactivity :

Canine

sequence length :

478

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Canine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LAMP2 (hereafter termed "analyte") in undiluted original Canine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

2498525

ncbi acc num :

Q14108.2

uniprot acc num :

Q14108

ncbi mol weight :

54,290 Da

ncbi pathways :

Lysosome Pathway (99052); Lysosome Pathway (96865)

ncbi summary :

The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]

uniprot summary :

SCARB2: Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting. Defects in SCARB2 are the cause of progressive myoclonic epilepsy type 4 with or without renal failure (EPM4). An autosomal recessive progressive myoclonic epilepsy associated with renal failure in some cases. Cognitive function is preserved. Myoclonus is a brief, involuntary twitching of a muscle or a group of muscles. Cognitive function is preserved. Genetic variants in SCARB2 can act as modifier of the phenotypic expression and severity of Gaucher disease. Belongs to the CD36 family. Protein type: Receptor, misc.; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 4q21.1. Cellular Component: lysosomal lumen; focal adhesion; membrane; lysosomal membrane; integral to membrane. Molecular Function: protein binding; enzyme binding; receptor activity. Biological Process: protein targeting to lysosome; cell adhesion. Disease: Epilepsy, Progressive Myoclonic 4, With Or Without Renal Failure

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095