ELISA/assay

Monkey Glucocorticoid Induced Tumor Necrosis Factor Receptor ELISA Kit

MBS064834

48-Strip-Wells

470 USD

ELISA Kit

Monkey Glucocorticoid Induced Tumor Necrosis Factor Receptor ELISA Kit

[Glucocorticoid Induced Tumor Necrosis Factor Receptor]

[glucocorticoid-induced TNFR-related protein; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily member 18; activation-inducible TNFR family receptor; glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation-inducible protein; tumor necrosis factor receptor superfamily, member 18; Activation-inducible TNFR family receptor; Glucocorticoid-induced TNFR-related protein]

[GITR]

[TNFRSF18; TNFRSF18; AITR; GITR; CD357; GITR-D; AITR; GITR]

TNR18_HUMAN

Monkey

241

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Assay Type: Quantitative Sandwich. Detection Range: 62.5 pg/ml - 2000 pg/ml. Sensitivity: 10 pg/ml

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GITR (hereafter termed "analyte") in undiluted original Monkey body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

4558503

AAD22635.1

Q9Y5U5

26,000 Da

Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Downstream Signaling In Naive CD8+ T Cells Pathway (138018)

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]

TNFRSF18: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Apoptosis; Receptor, cytokine. Chromosomal Location of Human Ortholog: 1p36.3. Cellular Component: integral to plasma membrane; extracellular region; external side of plasma membrane. Molecular Function: tumor necrosis factor receptor activity. Biological Process: tumor necrosis factor-mediated signaling pathway; apoptosis; signal transduction; negative regulation of apoptosis

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095