ELISA/assay

Mouse Uncoupling Protein 1, Mitochondrial ELISA Kit

MBS058911

48-Strip-Wells

470 USD

ELISA Kit

Mouse Uncoupling Protein 1, Mitochondrial ELISA Kit

[Uncoupling Protein 1, Mitochondrial]

[uncoupling family protein PUMP2; Mitochondrial uncoupling protein 1; uncoupling family protein PUMP2]

[UCP1]

[PUMP1; PUMP1; ARABIDOPSIS THALIANA PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 1; ARABIDOPSIS THALIANA UNCOUPLING PROTEIN 1; ATPUMP1; ATUCP1; plant uncoupling mitochondrial protein 1; PUMP1; UCP; UCP1; UNCOUPLING PROTEIN 1; UCP1; AtPUMP1]

PUMP1_ARATH

Mouse

306

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 62.5 pg/ml - 2000 pg/mL. Sensitivity: 10 pg/mL

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of UCP1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

15232420

NP_190979.1

NM_115271.4

O81845

32,662 Da

Metabolism Pathway (1007804); Mitochondrial Uncoupling Proteins Pathway (1007939); Respiratory Electron Transport, ATP Synthesis By Chemiosmotic Coupling, And Heat Production By Uncoupling Proteins. Pathway (1007937); The Citric Acid (TCA) Cycle And Respiratory Electron Transport Pathway (1007931); The Fatty Acid Cycling Model Pathway (1007940); The Proton Buffering Model Pathway (1007941)

Member of Uncoupling protein PUMP2 family. Encodes a mitochondrial uncoupling protein AtUCP1 involved in maintain the redox poise of the mitochondrial electron transport chain to facilitate photosynthetic metabolism. Disruption of UCP1 results in a photosynthetic phenotype. Specifically there is a restriction in photorespiration with a decrease in the rate of oxidation of photorespiratory glycine in the mitochondrion. This change leads to an associated reduced photosynthetic carbon assimilation rate.

Function: PUMPS are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. This leads to a decrease in the efficiency of oxidative phosphorylation and an increase in heat production. Is involved in protecting plant cells against oxidative stress damage and maintaining the redox balance of the mitochondrial electron transport chain to facilitate photosynthetic metabolism. May play a regulatory role during photorespiration. Ref.8 Ref.9 Ref.12 Ref.13 Ref.15 Ref.16. Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein . By similarity. Tissue specificity: Widely expressed. Ref.1 Ref.12. Induction: By cold stress, high light and chloramphenicol. Ref.1 Ref.10 Ref.14. Disruption phenotype: Slight reduction of shoot mass. Ref.12. Miscellaneous: Over-expression of Arabidopsis UCP1 in tobacco plants increases tolerance to oxidative stress caused by exogenous hydrogen peroxide, or by drought and salt (Ref.9). Sequence similarities: Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]Contains 3 Solcar repeats. Sequence caution: The sequence BAD95028.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095