catalog number :
MBS056318
products type :
ELISA Kit
products full name :
Camel A Disintegrin and Metalloprotease 8 ELISA Kit
products short name :
A Disintegrin and Metalloprotease 8
other names :
ADAM8 protein; Disintegrin and metalloproteinase domain-containing protein 8; disintegrin and metalloproteinase domain-containing protein 8; cell surface antigen MS2; human leukocyte differentiation antigen; a disintegrin and metalloproteinase domain 8; ADAM metallopeptidase domain 8; Cell surface antigen MS2
products gene name :
ADAM8
other gene names :
ADAM8; ADAM8; MS2; CD156; MS2; ADAM 8
uniprot entry name :
ADAM8_HUMAN
storage stability :
Store all reagents at 2-8 degree C
ncbi acc num :
AAI15405.1
ncbi mol weight :
88,771 Da
ncbi summary :
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]
uniprot summary :
Function: Possible involvement in extravasation of leukocytes. Cofactor: Binds 1 zinc ion per subunit. Subunit structure: Interacts with FST3. Ref.5. Subcellular location: Membrane; Single-pass type I membrane protein. Tissue specificity: Expressed on neutrophils and monocytes. Sequence similarities: Contains 1 disintegrin domain.Contains 1 EGF-like domain.Contains 1 peptidase M12B domain.