product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse Farnesyl Diphosphate Synthase ELISA Kit
catalog :
MBS054891
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS054891
products type :
ELISA Kit
products full name :
Mouse Farnesyl Diphosphate Synthase ELISA Kit
products short name :
[Farnesyl Diphosphate Synthase]
other names :
[Farnesyl pyrophosphate synthase; Farnesyl pyrophosphate synthase; farnesyl pyrophosphate synthase; FPP synthase; FPP synthetase; geranyltranstransferase; dimethylallyltranstransferase; (2E,6E)-farnesyl diphosphate synthase; farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase; farnesyl diphosphate synthase; (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase (EC:2.5.1.1); Farnesyl diphosphate synthase; Geranyltranstransferase]
products gene name :
[FDPS]
other gene names :
[FDPS; FDPS; FPS; FPPS; FPS; KIAA1293; FPP synthase; FPS]
uniprot entry name :
FPPS_HUMAN
reactivity :
Mouse
sequence length :
419
storage stability :
Store all reagents at 2-8 degree C
ncbi gi num :
215274250
ncbi acc num :
P14324.4
uniprot acc num :
P14324
ncbi mol weight :
48,275 Da
ncbi pathways :
Activation Of Gene Expression By SREBF (SREBP) Pathway (685552); Cholesterol Biosynthesis Pathway (198809); Cholesterol Biosynthesis Pathway (106142); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); Influenza A Pathway (217173); Influenza A Pathway (217150); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Regulation Of Cholesterol Biosynthesis By SREBP (SREBF) Pathway (685551)
ncbi summary :
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]
uniprot summary :
FDPS: Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. Belongs to the FPP/GGPP synthase family. Protein type: Motility/polarity/chemotaxis; EC 2.5.1.1; EC 2.5.1.10; Transferase; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis. Chromosomal Location of Human Ortholog: 1q22. Cellular Component: nucleoplasm; mitochondrion; cytoplasm; cytosol. Molecular Function: geranyltranstransferase activity; dimethylallyltranstransferase activity; metal ion binding. Biological Process: viral reproduction; geranyl diphosphate biosynthetic process; farnesyl diphosphate biosynthetic process; cholesterol biosynthetic process
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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