catalog number :
MBS049767
products type :
ELISA Kit
products full name :
Canine Urocortin 2 ELISA Kit
products short name :
[Urocortin 2]
other names :
[urocortin preproprotein; Urocortin; urocortin; prepro-urocortin; urocortin, preproprotein; urocortin]
products gene name :
[UCN2]
other gene names :
[UCN; UCN; UI; UROC]
uniprot entry name :
UCN1_HUMAN
storage stability :
Store all reagents at 2-8 degree C
ncbi acc num :
NP_003344.1
ncbi gb acc num :
NM_003353.2
ncbi mol weight :
13,458 Da
ncbi summary :
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]
uniprot summary :
UCN: Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH). Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta. Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 2p23.3. Cellular Component: dendrite; extracellular region; perikaryon; nerve terminal. Molecular Function: corticotropin-releasing hormone receptor 1 binding; histone deacetylase inhibitor activity; neuropeptide hormone activity; protein binding; corticotropin-releasing hormone receptor 2 binding. Biological Process: regulation of synaptic transmission, glutamatergic; positive regulation of translation; negative regulation of hormone secretion; positive regulation of collagen biosynthetic process; response to glucocorticoid stimulus; drinking behavior; response to pain; negative regulation of cell size; female pregnancy; positive regulation of vasodilation; pancreatic juice secretion; response to estradiol stimulus; negative regulation of appetite; positive regulation of adrenocorticotropic hormone secretion; sensory perception of sound; neuropeptide signaling pathway; positive regulation of cAMP biosynthetic process; negative regulation of blood pressure; inflammatory response; neurite development; associative learning; negative regulation of histone deacetylation; activation of protein kinase A; positive regulation of interleukin-6 production; social behavior; positive regulation of cell growth; positive regulation of peptidyl-serine phosphorylation; positive regulation of vascular permeability; G-protein coupled receptor protein signaling pathway; aerobic respiration; response to oxidative stress; positive regulation of DNA replication; negative regulation of apoptosis
size4 :
10x96-Strip-Wells