catalog number :
MBS049495
products type :
ELISA Kit
products full name :
Human Aldehyde Dehydrogenase 3 Family, Member A1 ELISA Kit
products short name :
[Aldehyde Dehydrogenase 3 Family, Member A1]
other names :
[aldehyde dehydrogenase family 8 member A1 isoform 3; Aldehyde dehydrogenase family 8 member A1; aldehyde dehydrogenase family 8 member A1; aldehyde dehydrogenase 12; aldehyde dehydrogenase family protein; aldehyde dehydrogenase 8 family, member A1; Aldehyde dehydrogenase 12]
products gene name :
[ALDH3A1]
other gene names :
[ALDH8A1; ALDH8A1; ALDH12; DJ352A20.2; ALDH12]
uniprot entry name :
AL8A1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich (Quantitative). Detection Range: 1.56 ng/ml - 50 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ALDH3A1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001180409.1
ncbi gb acc num :
NM_001193480.1
ncbi mol weight :
53,401 Da
ncbi summary :
This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene. [provided by RefSeq, Jul 2010]
uniprot summary :
ALDH8A1: Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD, but shows considerable activity with NADP (in vitro). Belongs to the aldehyde dehydrogenase family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: EC 1.2.1.-; Oxidoreductase. Chromosomal Location of Human Ortholog: 6q23.2. Cellular Component: cytoplasm; intracellular. Molecular Function: aldehyde dehydrogenase (NAD) activity; retinal dehydrogenase activity. Biological Process: retinal metabolic process; 9-cis-retinoic acid biosynthetic process; retinoic acid metabolic process
size4 :
10x96-Strip-Wells