Cat Retinol Binding Protein 4 ELISA Kit | MyBioSource MBS048954 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Cat Retinol Binding Protein 4 ELISA Kit

catalog :

MBS048954

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS048954

products type :

ELISA Kit

products full name :

Cat Retinol Binding Protein 4 ELISA Kit

products short name :

[Retinol Binding Protein 4]

other names :

[retinol-binding protein 4; Retinol-binding protein 4; retinol-binding protein 4; RBP; PRBP; plasma retinol-binding protein; retinol-binding protein 4, interstitial; retinol binding protein 4, plasma; Plasma retinol-binding protein]

products gene name :

[RBP4]

other gene names :

[RBP4; RBP4; RDCCAS; PRBP; RBP]

uniprot entry name :

RET4_HUMAN

reactivity :

Cat

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 3.12 ug/ml - 100 ug/ml. Sensitivity: 1.0 ug/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RBP4 (hereafter termed this analyte) in undiluted original Cat serum, plasma and tissue homogenate samples.

ncbi gi num :

55743122

ncbi acc num :

NP_006735.2

ncbi gb acc num :

NM_006744.3

uniprot acc num :

P02753

ncbi mol weight :

23,010 Da

ncbi pathways :

Disease Pathway (530764); Diseases Associated With Visual Transduction Pathway (771581); Retinoid Cycle Disease Events Pathway (771582); Retinoid Metabolism And Transport Pathway (187208); SREBP Signalling Pathway (219802); Signal Transduction Pathway (477114); The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway (771585); Visual Phototransduction Pathway (771584); Vitamin A And Carotenoid Metabolism Pathway (198785); Retinoate Biosynthesis I Pathway (545452)

ncbi summary :

This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008]

uniprot summary :

RBP4: Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli. Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency). This condition causes night vision problems. It produces a typical fundus xerophthalmicus , featuring a progressed atrophy of the retinal pigment epithelium. Belongs to the calycin superfamily. Lipocalin family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 10q23.33. Cellular Component: extracellular space; protein complex; extracellular region; cytosol. Molecular Function: protein binding; protein heterodimerization activity; retinol binding; retinal binding. Biological Process: phototransduction, visible light; retinal metabolic process; embryonic skeletal development; maintenance of gastrointestinal epithelium; heart development; glucose homeostasis; uterus development; response to insulin stimulus; embryonic organ morphogenesis; retinol metabolic process; negative regulation of cardiac muscle cell proliferation; detection of light stimulus involved in visual perception; retinoid metabolic process; female genitalia morphogenesis; cardiac muscle development; response to retinoic acid; urinary bladder development; male gonad development; vagina development; positive regulation of insulin secretion; positive regulation of immunoglobulin secretion; gluconeogenesis; response to ethanol; eye development; embryonic retina morphogenesis in camera-type eye; spermatogenesis; lung development. Disease: Retinal Dystrophy, Iris Coloboma, And Comedogenic Acne Syndrome; Microphthalmia, Isolated, With Coloboma 10

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095