catalog number :
MBS047236
products type :
ELISA Kit
products full name :
Bovine Relaxin ELISA Kit
products short name :
Relaxin
other names :
relaxin; Prorelaxin H1; prorelaxin H1; preprorelaxin H1; relaxin 1
other gene names :
RLN1; RLN1; H1; H1RLX; RLXH1; bA12D24.3.1; bA12D24.3.2
uniprot entry name :
REL1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml. Assay Type: Sandwich
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RLN (hereafter termed this analyte) in undiluted original Bovine serum, plasma and tissue homogenate samples.
ncbi acc num :
CAA00599.1
ncbi mol weight :
21,146 Da
ncbi pathways :
Androgen Receptor Signaling Pathway (198806); Myometrial Relaxation And Contraction Pathways (198759)
ncbi summary :
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013]
uniprot summary :
RLN1: Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix. Belongs to the insulin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 9p24.1. Cellular Component: extracellular region. Molecular Function: hormone activity. Biological Process: female pregnancy; signal transduction