catalog number :
MBS047141
products type :
ELISA Kit
products full name :
Horse Syndecan-1/Cd138 ELISA Kit
products short name :
[Syndecan-1/Cd138]
other names :
[syndecan-1; Syndecan-1; syndecan-1; CD138 antigen; syndecan proteoglycan 1; heparan sulfate proteoglycan fibroblast growth factor receptor; syndecan 1]
products gene name :
[SDC1/CD138]
other gene names :
[SDC1; SDC1; SDC; CD138; SYND1; syndecan; SDC; SYND1]
uniprot entry name :
SDC1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Rabbit Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 6.25ug/ml-200ug/ml. Sensitivity: 1.0ug/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of SDC1/CD138 (hereafter termed "analyte") in undiluted original Rabbit serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001006947.1
ncbi gb acc num :
NM_001006946.1
ncbi mol weight :
32,462 Da
ncbi pathways :
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway (645305); Arf6 Trafficking Events Pathway (137954); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Chylomicron-mediated Lipid Transport Pathway (106157); Disease Pathway (530764); Diseases Associated With Visual Transduction Pathway (771581); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479)
ncbi summary :
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]
uniprot summary :
syndecan-1: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Belongs to the syndecan proteoglycan family. Protein type: Motility/polarity/chemotaxis; Extracellular matrix; Membrane protein, integral. Chromosomal Location of Human Ortholog: 2p24.1. Cellular Component: lysosomal lumen; cell surface; focal adhesion; protein complex; Golgi lumen; integral to plasma membrane; cytoplasm; plasma membrane; external side of plasma membrane. Molecular Function: protein C-terminus binding; protein binding; glycoprotein binding. Biological Process: phototransduction, visible light; extracellular matrix organization and biogenesis; response to cAMP; myoblast development; wound healing; glycosaminoglycan metabolic process; striated muscle cell development; response to toxin; response to glucocorticoid stimulus; pathogenesis; lipoprotein metabolic process; Wnt receptor signaling pathway through beta-catenin; Sertoli cell development; chondroitin sulfate metabolic process; odontogenesis; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; response to hydrogen peroxide; ureteric bud development; carbohydrate metabolic process; inflammatory response; retinoid metabolic process; response to calcium ion
size4 :
10x96-Strip-Wells