Rat Prostaglandin D2 Synthase, Brain ELISA Kit | MyBioSource MBS046846 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rat Prostaglandin D2 Synthase, Brain ELISA Kit

catalog :

MBS046846

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS046846

products type :

ELISA Kit

products full name :

Rat Prostaglandin D2 Synthase, Brain ELISA Kit

products short name :

[Prostaglandin D2 Synthase, Brain]

other names :

[prostaglandin-H2 D-isomerase; Prostaglandin-H2 D-isomerase; prostaglandin-H2 D-isomerase; cerebrin-28; PGD2 synthase; beta-trace protein; prostaglandin D synthase; prostaglandin-D2 synthase; glutathione-independent PGD synthase; glutathione-independent PGD synthetase; lipocalin-type prostaglandin D synthase; lipocalin-type prostaglandin-D synthase; prostaglandin D2 synthase 21kDa (brain); Beta-trace protein; Cerebrin-28; Glutathione-independent PGD synthase; Lipocalin-type prostaglandin-D synthase; Prostaglandin-D2 synthase]

products gene name :

[PGD2S]

other gene names :

[PTGDS; PTGDS; PDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS; PDS; PGD2 synthase; PGDS; PGDS2]

uniprot entry name :

PTGDS_HUMAN

reactivity :

Rat

sequence length :

190

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Assay Type: Quantitative Sandwich. Detection Range: 1.25ng/ml-40ng/ml. Sensitivity: 0.1ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PGD2S (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

32171249

ncbi acc num :

NP_000945.3

ncbi gb acc num :

NM_000954.5

uniprot acc num :

P41222

ncbi mol weight :

21,029 Da

ncbi pathways :

Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (685553); Arachidonic Acid Metabolism Pathway (366); C20 Prostanoid Biosynthesis Pathway (908107); Eicosanoid Synthesis Pathway (198888); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Prostaglandin Synthesis And Regulation Pathway (198912); Synthesis Of Prostaglandins (PG) And Thromboxanes (TX) Pathway (730333); Prostanoid Biosynthesis Pathway (545299)

ncbi summary :

The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008]

uniprot summary :

PTGDS: Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. Belongs to the calycin superfamily. Lipocalin family. Protein type: Lipid Metabolism - arachidonic acid; Secreted, signal peptide; Endoplasmic reticulum; EC 5.3.99.2; Isomerase; Secreted. Chromosomal Location of Human Ortholog: 9q34.2-q34.3. Cellular Component: Golgi apparatus; extracellular space; endoplasmic reticulum membrane; nuclear membrane; rough endoplasmic reticulum; perinuclear region of cytoplasm; extracellular region. Molecular Function: retinoid binding; prostaglandin-D synthase activity; transporter activity; fatty acid binding. Biological Process: transport; response to glucocorticoid stimulus; cyclooxygenase pathway; arachidonic acid metabolic process; prostaglandin biosynthetic process; regulation of circadian sleep/wake cycle, sleep

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095