catalog number :
MBS046641
products type :
ELISA Kit
products full name :
Rat Glypican 4 ELISA Kit
products short name :
[Glypican 4]
other names :
[glypican-4; Glypican-4; glypican-4; dJ900E8.1 (glypican 4); glypican proteoglycan 4; glypican 4; K-glypican]
products gene name :
[GPC4]
other gene names :
[GPC4; GPC4; K-glypican]
uniprot entry name :
GPC4_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GPC4 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001439.2
ncbi gb acc num :
NM_001448.2
ncbi mol weight :
62,412 Da
ncbi pathways :
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway (645305); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Disease Pathway (530764); Diseases Associated With Visual Transduction Pathway (771581); Glycosaminoglycan Metabolism Pathway (645297); HS-GAG Biosynthesis Pathway (645306); HS-GAG Degradation Pathway (645307); Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway (645304); MPS I - Hurler Syndrome Pathway (685537); MPS II - Hunter Syndrome Pathway (685538)
ncbi summary :
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome. [provided by RefSeq, Jul 2008]
uniprot summary :
GPC4: Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system. Belongs to the glypican family. Protein type: Motility/polarity/chemotaxis; Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: Xq26.1. Cellular Component: extracellular space; lysosomal lumen; proteinaceous extracellular matrix; Golgi lumen; integral to plasma membrane; plasma membrane; nucleus; external side of plasma membrane. Molecular Function: heparan sulfate proteoglycan binding. Biological Process: chondroitin sulfate metabolic process; cell proliferation; glycosaminoglycan biosynthetic process; phototransduction, visible light; glycosaminoglycan catabolic process; anatomical structure morphogenesis; glycosaminoglycan metabolic process; carbohydrate metabolic process; pathogenesis; retinoid metabolic process. Disease: Simpson-golabi-behmel Syndrome, Type 1; Wilms Tumor 1
size4 :
10x96-Strip-Wells