catalog number :
MBS045841
products type :
ELISA Kit
products full name :
Human Histatin 5 ELISA Kit
products short name :
Histatin 5
other names :
histatin-3; Histatin-3; histatin-3; PB; hst; histatin 5; histidine-rich protein 3; basic histidine-rich protein; histatin 3; Basic histidine-rich protein; Hst; Histidine-rich protein 3; PBCleaved into the following 26 chains:Histatin-3His3-(20-44)-peptide; His3 20/44; Alternative name(s):; His3-(1-25)-peptide; His3 1/25; Histatin-3 1/25; Histatin-6His3-(20-43)-peptide; His3 20/43; Alternative name(s):; His3-(1-24)-peptide; His3 1/24; Histatin-3 1/24; Histatin-5His3-(20-32)-peptide; His3 20/32; Alternative name(s):; His3-(1-13)-peptide; His3 1/13; Histatin-3 1/13His3-(20-31)-peptide; His3 20/31; Alternative name(s):; His3-(1-12)-peptide; His3 1/12; Histatin-3 1/12His3-(20-30)-peptide; His3 20/30; Alternative name(s):; His3-(1-11)-peptide; His3 1/11; Histatin-3 1/11His3-(24-32)-peptide; His3 24/32; Alternative name(s):; His3-(5-13)-peptide; His3 5/13; Histatin-3 5/13His3-(24-31)-peptide; His3 24/31; Alternative name(s):; His3-(5-12)-peptide; His3 5/12; Histatin-11; Histatin-3 5/12His3-(24-30)-peptide; His3 24/30; Alternative name(s):; His3-(5-11)-peptide; His3 5/11; Histatin-12; Histatin-3 5/11His3-(25-32)-peptide; His3 25/32; Alternative name(s):; His3-(6-13)-peptide; His3 6/13; Histatin-3 6/13His3-(25-30)-peptide; His3 25/30; Alternative name(s):; His3-(6-11)-peptide; His3 6/11; Histatin-3 6/11His3-(26-32)-peptide; His3 26/32; Alternative name(s):; His3-(7-13)-peptide; His3 7/13; Histatin-3 7/13His3-(26-31)-peptide; His3 26/31; Alternative name(s):; His3-(7-12)-peptide; His3 7/12; Histatin-3 7/12His3-(26-30)-peptide; His3 26/30; Alternative name(s):; His3-(7-11)-peptide; His3 7/11; Histatin-3 7/11His3-(31-51)-peptide; His3 31/51; Alternative name(s):; His3-(12-32)-peptide; His3 12/32; Histatin-3 12/32; Histatin-4His3-(31-44)-peptide; His3 31/44; Alternative name(s):; His3-(12-25)-peptide; His3 12/25; Histatin-3 12/25; Histatin-9His3-(31-43)-peptide; His3 31/43; Alternative name(s):; His3-(12-24)-peptide; His3 12/24; Histatin-3 12/24; Histatin-7His3-(32-44)-peptide; His3 32/44; Alternative name(s):; His3-(13-25)-peptide; His3 13/25; Histatin-10; Histatin-3 13/25His3-(32-43)-peptide; His3 32-43; Alternative name(s):; His3-(13-24)-peptide; His3 13/24; Histatin-3 13/24; Histatin-8His3-(33-44)-peptide; His3 33/44; Alternative name(s):; His3-(14-25)-peptide; His3 14/25; Histatin-3 14/25His3-(33-43)-peptide; His3 33/43; Alternative name(s):; His3-(14-24)-peptide; His3 14/24; Histatin-3 14/24His3-(34-44)-peptide; His3 34/44; Alternative name(s):; His3-(15-25)-peptide; His3 15/25; Histatin-3 15/25His3-(34-43)-peptide; His3 34/43; Alternative name(s):; His3-(15-24)-peptide; His3 15/24; Histatin-3 15/24His3-(45-51)-peptide; His3 45/51; Alternative name(s):; His3-(26-32)-peptide; His3 26/32; Histatin-3 26/32His3-(47-51)-peptide; His3 47/51; Alternative name(s):; His3-(28-32)-peptide; His3 28/32; Histatin-3 28/32His3-(48-51)-peptide; His3 48/51; Alternative name(s):; His3-(29-32)-peptide; His3 29/32; Histatin-3 29/32
products gene name :
HTN5
other gene names :
HTN3; HTN3; HIS2; HTN2; HTN5; HIS2; Hst; His3 20/44; His3 1/25; His3 20/43; His3 1/24; His3 20/32; His3 1/13; His3 20/31; His3 1/12; His3 20/30; His3 1/11; His3 24/32; His3 5/13; His3 24/31; His3 5/12; His3 24/30; His3 5/11; His3 25/32; His3 6/13; His3 25/30; His3 6/11; His3 26/32; Hi
uniprot entry name :
HIS3_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
ELISA Type: Sandwich
ncbi acc num :
NP_000191.1
ncbi gb acc num :
NM_000200.2
ncbi mol weight :
6,149 Da
ncbi pathways :
Salivary Secretion Pathway 153376!!Salivary Secretion Pathway 153352
ncbi summary :
This gene encodes a member of the histatin family of small, histidine-rich salivary proteins. Histatins exhibit non-immunological, anti-microbial activity in the oral cavity. [provided by RefSeq, May 2009]
uniprot summary :
Function: Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. His3-(20-43)-peptide (histatin-5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9. Ref.10 Ref.12. Subunit structure: His3-(20-43)-peptide is a homodimer. Histatin-3 and His3-(20-43)-peptide interact with yeast SSA1 and SSA2 proteins. Subcellular location: Secreted. Note: Secreted by serous acinar and demilune cells. Ref.14. Post-translational modification: 24 proteolytic products are found in saliva. Polymorphism: There are two alleles of HTN3, HIS21 (shown here) and HIS22 that codes for the variant histatin-3-2 found primarily and in high frequencies in black populations. Miscellaneous: The recommended nomenclature of salivary peptides follows published guidelines (Ref.16). In agreement with the authors, it has been decided to indicate the boundaries of the peptides according to the positions within the precursor, and not in the mature protein, as has formerly been proposed. Sequence similarities: Belongs to the histatin/statherin family.