Mouse Placental Lactogen ELISA Kit | MyBioSource MBS045799 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Placental Lactogen ELISA Kit

catalog :

MBS045799

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS045799

products type :

ELISA Kit

products full name :

Mouse Placental Lactogen ELISA Kit

products short name :

Placental Lactogen

other names :

placental lactogen; Chorionic somatomammotropin hormone; chorionic somatomammotropin hormone; choriomammotropin; placental lactogen; chorionic somatomammotropin A; chorionic somatomammotropin hormone 1 (placental lactogen); Lactogen; Placental lactogen

products gene name :

other gene names :

CSH1; CSH1; PL; CSA; CS-1; CSMT; hCS-A; Choriomammotropin; PL

uniprot entry name :

CSH_HUMAN

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between Mouse PL and analogues was observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.

other info2 :

Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated PL concentrations in Mouse serum, plasma and other body fluids. Using Purified Mouse PL antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add PL and PL antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of PL in the samples is then determined by comparing the O.D. of the samples to the standard curve. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated PL concentrations in Mouse serum, plasma and other body fluids. Using Purified Mouse PL antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add PL and PL antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of PL in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

190034

ncbi acc num :

AAA98621.1

uniprot acc num :

P01243

ncbi mol weight :

25,020 Da

ncbi pathways :

Cytokine Signaling In Immune System Pathway (366171); Growth Hormone Receptor Signaling Pathway (477128); Immune System Pathway (106386); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Nuclear Signaling By ERBB4 Pathway (530744); PI3K-Akt Signaling Pathway (692234); PI3K-Akt Signaling Pathway (692979)

ncbi summary :

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008]

uniprot summary :

CSH1: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. Belongs to the somatotropin/prolactin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 17q24.2. Cellular Component: extracellular region. Molecular Function: metal ion binding; hormone activity

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage