catalog number :
MBS045652
products type :
ELISA Kit
products full name :
Human Aquaporin 1 ELISA Kit
products short name :
[Aquaporin 1]
other names :
[aquaporin-1; Aquaporin-1; aquaporin-1; DER2; AQP-1; aquaporin-CHIP; delayed early response protein 2; growth factor-induced delayed early response protein; water channel protein for red blood cells and kidney proximal tubule; aquaporin 1; Aquaporin-CHIP; Delayed early response protein 2; DER2; Water channel protein for red blood cells and kidney proximal tubule]
products gene name :
[AQP-1]
other gene names :
[Aqp1; Aqp1; CHIP28; AQP-1; DER2]
uniprot entry name :
AQP1_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Body Fluids, Tissue Homogenates, Secretions Or Feces Samples. Assay Type: Quantitative Sandwich. Detection Range: 15.6ng/ml-500ng/ml. Sensitivity: 2.0ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of APPB (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_031498.1
ncbi gb acc num :
NM_007472.2
ncbi mol weight :
28,793 Da
ncbi pathways :
Aquaporin-mediated Transport Pathway (819190); Bile Secretion Pathway (193148); Bile Secretion Pathway (193095); Metabolism Pathway (819200); O2/CO2 Exchange In Erythrocytes Pathway (819449); Passive Transport By Aquaporins Pathway (819191); Proximal Tubule Bicarbonate Reclamation Pathway (144184); Proximal Tubule Bicarbonate Reclamation Pathway (144027); Regulation Of Water Balance By Renal Aquaporins Pathway (819192); Transmembrane Transport Of Small Molecules Pathway (819149)
uniprot summary :
AQP1: Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Belongs to the MIP/aquaporin (TC 1.A.8) family. Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, aquaporin family. Cellular Component: neuron projection; nuclear membrane; basolateral plasma membrane; cell; integral to plasma membrane; brush border membrane; integral to membrane; dense core granule membrane; membrane; apical part of cell; axon; apical plasma membrane; cytoplasm; basal plasma membrane; plasma membrane; nerve terminal; nucleus; sarcolemma; brush border. Molecular Function: ephrin receptor binding; potassium channel activity; water transporter activity; ammonium transmembrane transporter activity; transporter activity; intracellular cGMP activated cation channel activity; glycerol transmembrane transporter activity; potassium ion transmembrane transporter activity; nitric oxide transporter activity; transmembrane transporter activity; water channel activity; glycerol channel activity. Biological Process: glycerol transport; cGMP biosynthetic process; wound healing; cellular response to stress; water transport; carbon dioxide transport; negative regulation of caspase activity; sensory perception of pain; positive regulation of saliva secretion; water homeostasis; positive regulation of fibroblast proliferation; organic cation transport; nitric oxide transport; transport; cellular homeostasis; transmembrane transport; potassium ion transport; lipid digestion; secretion by cell; response to drug; cellular water homeostasis; secretory granule organization and biogenesis; glomerular filtration; ammonium transport; positive regulation of angiogenesis; renal water transport; camera-type eye morphogenesis; adrenocorticotropin hormone secretion; establishment and/or maintenance of actin cytoskeleton polarity; cell volume homeostasis; positive regulation of cell migration; negative regulation of apoptosis
size4 :
10x96-Strip-Wells