catalog number :
MBS044705
products type :
ELISA Kit
products full name :
Sheep Amphiregulin ELISA Kit
products short name :
[Amphiregulin]
other names :
[amphiregulin preproprotein; Amphiregulin; amphiregulin; schwannoma-derived growth factor; colorectum cell-derived growth factor; amphiregulin; Colorectum cell-derived growth factor]
products gene name :
[AREG]
other gene names :
[AREG; AREG; AR; SDGF; CRDGF; SDGF; AR; CRDGF]
uniprot entry name :
AREG_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of AREG (hereafter termed "analyte") in undiluted original Sheep body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001648.1
ncbi gb acc num :
NM_001657.2
ncbi mol weight :
27,895 Da
ncbi pathways :
ErbB Receptor Signaling Network Pathway (138016); ErbB Signaling Pathway (198844); ErbB Signaling Pathway (83049); ErbB Signaling Pathway (458); FSH Signaling Pathway (672455); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388)
ncbi summary :
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype. [provided by RefSeq, Jul 2008]
uniprot summary :
AREG: Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts. Belongs to the amphiregulin family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular space; cell surface; cytoplasm; integral to membrane; nucleus. Molecular Function: protein binding; growth factor activity; cytokine activity; epidermal growth factor receptor binding. Biological Process: epidermal growth factor receptor signaling pathway; response to peptide hormone stimulus; response to cAMP; response to glucocorticoid stimulus; response to estradiol stimulus; glial cell proliferation; cell proliferation; G-protein coupled receptor protein signaling pathway; response to hydrogen peroxide; cell-cell signaling; positive regulation of cell proliferation; negative regulation of osteoblast differentiation; positive regulation of DNA replication; neurite development; positive regulation of phosphorylation
size4 :
10x96-Strip-Wells