catalog number :
MBS044575
products type :
ELISA Kit
products full name :
Rat Soluble Cluster of Differentiation 40 Ligand ELISA Kit
products short name :
Soluble Cluster of Differentiation 40 Ligand
other names :
Sodium/hydrogen exchanger 10; Sodium/hydrogen exchanger 10; sodium/hydrogen exchanger 10; sNHE; NHE-10; Na(+)/H(+) exchanger 10; solute carrier family 9 member C1; solute carrier family 10 member 10; solute carrier family 9, member 10; solute carrier family 9, isoform 10; sperm-specific Na(+)/H(+) exchanger; sperm-specific sodium proton exchanger; solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1; Na(+)/H(+) exchanger 10; NHE-10; Solute carrier family 9 member 10; Solute carrier family 9 member C1; Sperm-specific Na(+)/H(+) exchanger
products gene name :
SCD40L
other gene names :
SLC9C1; SLC9C1; NHE; SLC9A10; sperm-NHE; SLC9A10; NHE-10; sNHE
uniprot entry name :
SL9C1_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich
ncbi mol weight :
135,206 Da
ncbi pathways :
Ion Channel Transport Pathway (187193); Stimuli-sensing Channels Pathway (771568); Transmembrane Transport Of Small Molecules Pathway (106572)
ncbi summary :
SLC9A10 is a member of the sodium-hydrogen exchanger (NHE) family (see SLC9A1, MIM 107310) and is required for male fertility and sperm motility (Wang et al., 2003 [PubMed 14634667]).[supplied by OMIM, Apr 2009]
uniprot summary :
NHE10: Sperm-specific sodium/hydrogen exchanger involved in intracellular pH regulation of spermatozoa. Required for sperm motility and fertility. Involved in sperm cell hyperactivation, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for the expression and bicarbonate regulation of the soluble adenylyl cyclase (sAC). Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Transporter, ion channel; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 3q13.2. Cellular Component: plasma membrane; integral to membrane. Molecular Function: solute:hydrogen antiporter activity. Biological Process: sperm motility; multicellular organismal development; sodium ion transport; spermatogenesis; cell differentiation; transmembrane transport