ELISA/assay

Human Netrin-1 ELISA Kit

MBS044526

48-Strip-Wells

435 USD

ELISA Kit

Human Netrin-1 ELISA Kit

Netrin-1

netrin-1; Netrin-1; netrin-1; netrin 1, mouse, homolog of; epididymis tissue protein Li 131P; netrin 1; Epididymis tissue protein Li 131P

NTN1

NTN1; NTN1; NTN1L; NTN1L

NET1_HUMAN

Human

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 3.12 pg/ml - 100 pg/ml. Sensitivity: 1.0 pg/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of NTN1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

148613884

NP_004813.2

NM_004822.2

O95631

67,748 Da

Alpha6-Beta4 Integrin Signaling Pathway (198807); Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (105688); Cell-Cell Communication Pathway (477132); DCC Mediated Attractive Signaling Pathway (161000); DSCAM Interactions Pathway (187229); Developmental Biology Pathway (477129); Netrin Mediated Repulsion Signals Pathway (161001); Netrin-1 Signaling Pathway (160999)

Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development. [provided by RefSeq, Jul 2008]

NTN1: Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 17p13.1. Cellular Component: cytoplasm; extracellular region; basement membrane. Molecular Function: protein binding. Biological Process: axon guidance; inner ear morphogenesis; cell-cell adhesion; establishment of nucleus localization; apoptosis; positive regulation of axon extension; positive regulation of cell proliferation; neuron migration; negative regulation of axon extension; regulation of cell migration; anterior/posterior axon guidance

48-Strip-Wells

435 USD

96-Strip-Wells

600