ELISA/assay

Fish Estradiol, E2 ELISA Kit

MBS044518

48-Strip-Wells

435 USD

ELISA Kit

Fish Estradiol, E2 ELISA Kit

Estradiol, E2

estradiol 17-beta-dehydrogenase 12; Estradiol 17-beta-dehydrogenase 12; estradiol 17-beta-dehydrogenase 12; 17-beta-HSD 12; 17beta-HSD type 12; 3-ketoacyl-CoA reductase; steroid dehydrogenase homolog; 17-beta-hydroxysteroid dehydrogenase 12; short chain dehydrogenase/reductase family 12C, member 1; hydroxysteroid (17-beta) dehydrogenase 12; 17-beta-hydroxysteroid dehydrogenase 12; 17-beta-HSD 12; 3-ketoacyl-CoA reductase

E2

HSD17B12; HSD17B12; KAR; SDR12C1; 17-beta-HSD 12; KAR

DHB12_HUMAN

Fish

312

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Undiluted original Fish body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 6.25pg/ml-200pg/ml. Sensitivity: 1.0pg/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of E2 (hereafter termed "analyte") in undiluted original Fish body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

7705855

NP_057226.1

NM_016142.2

Q53GQ0

34,324 Da

Androgen Biosynthesis Pathway (106154); Biosynthesis Of Unsaturated Fatty Acids Pathway (83034); Biosynthesis Of Unsaturated Fatty Acids Pathway (429); Fatty Acyl-CoA Biosynthesis Pathway (106115); Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway (413482); Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway (468402); Fatty Acid Elongation Pathway (82934); Fatty Acid Elongation Pathway (295); Fatty Acid Metabolism Pathway (868084); Fatty Acid Metabolism Pathway (878045)

This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. [provided by RefSeq, Oct 2011]

HSD17B12: Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women. Also has 3-ketoacyl-CoA reductase activity, reducing both long chain 3-ketoacyl-CoAs and long chain fatty acyl-CoAs, suggesting a role in long fatty acid elongation. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily. Protein type: Membrane protein, multi-pass; Lipid Metabolism - androgen and estrogen; Membrane protein, integral; Lipid Metabolism - unsaturated fatty acid biosynthesis; EC 1.1.1.62; Oxidoreductase. Chromosomal Location of Human Ortholog: 11p11.2. Cellular Component: extracellular matrix; endoplasmic reticulum membrane; integral to membrane. Molecular Function: collagen binding; heparin binding; estradiol 17-beta-dehydrogenase activity; protein binding; fibronectin binding. Biological Process: extracellular matrix organization and biogenesis; triacylglycerol biosynthetic process; cellular lipid metabolic process; estrogen biosynthetic process; fatty acid biosynthetic process

48-Strip-Wells

435 USD

96-Strip-Wells

600