catalog number :
MBS044348
products type :
ELISA Kit
products full name :
Human Complement Component 9 ELISA Kit
products short name :
[Complement Component 9]
other names :
[complement component 9; Complement component 9; complement component C9; complement component 9]
products gene name :
[C9]
other gene names :
[C9; C9]
uniprot entry name :
Q9UGI4_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Mouse Body Fluids, Tissue Homogenates, Secretions Or Feces Samples. Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml-100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of C5ORF13 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
CAB66087.1
ncbi mol weight :
2,706 Da
ncbi pathways :
Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Complement Activation, Classical Pathway (198823); Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Complement Cascade Pathway (106405); Immune System Pathway (106386); Innate Immune System Pathway (106387); Prion Diseases Pathway (101144)
ncbi summary :
This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009]
uniprot summary :
C9: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. Defects in C9 are a cause of complement component 9 deficiency (C9D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family. Protein type: Membrane protein, integral; Extracellular matrix; Membrane protein, multi-pass; Apoptosis. Chromosomal Location of Human Ortholog: 5p14-p12. Cellular Component: membrane attack complex; integral to plasma membrane; cytoplasm; extracellular region; plasma membrane. Biological Process: complement activation, alternative pathway; regulation of complement activation; innate immune response; hemolysis by symbiont of host red blood cells; complement activation, classical pathway. Disease: Macular Degeneration, Age-related, 15; Complement Component 9 Deficiency
size4 :
10x96-Strip-Wells