Human Growth Differentiation Factor 11 ELISA Kit | MyBioSource MBS044093 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Growth Differentiation Factor 11 ELISA Kit

catalog :

MBS044093

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS044093

products type :

ELISA Kit

products full name :

Human Growth Differentiation Factor 11 ELISA Kit

products short name :

Growth Differentiation Factor 11

other names :

growth/differentiation factor 11; Growth/differentiation factor 11; growth/differentiation factor 11; GDF-11; bone morphogenetic protein 11; growth differentiation factor 11; Bone morphogenetic protein 11

products gene name :

GDF11

other gene names :

GDF11; GDF11; BMP11; BMP-11; BMP11; GDF-11; BMP-11

uniprot entry name :

GDF11_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between Human GDF11 and analogues was observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma, Tissue Homogenate, Feces and Urine. Assay Type: Sandwich. Detection Range: 62.5 pg/ml - 2000 pg/ml. Sensitivity: 10 pg/ml.

other info2 :

Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated GDF11 concentrations in Human serum, plasma and other body fluids. Using Purified Human GDF11 antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add GDF11 and GDF11 antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of GDF11 in the samples is then determined by comparing the O.D. of the samples to the standard curve. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated GDF11 concentrations in Human serum, plasma and other body fluids. Using Purified Human GDF11 antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add GDF11 and GDF11 antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of GDF11 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

5031613

ncbi acc num :

NP_005802.1

ncbi gb acc num :

NM_005811.3

uniprot acc num :

O95390

ncbi mol weight :

45,091 Da

ncbi summary :

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development. [provided by RefSeq, Jul 2008]

uniprot summary :

GDF11: Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Belongs to the TGF-beta family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 12q13.2. Cellular Component: extracellular space. Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding. Biological Process: nervous system development; cell maturation; palate development; regulation of apoptosis; negative regulation of cell proliferation; negative regulation of cell differentiation; camera-type eye morphogenesis; spinal cord anterior/posterior patterning; ureteric bud development; regulation of MAPKKK cascade; pancreas development; mesoderm development; skeletal development; metanephros development; cell development; growth

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage