Human Haptoglobin Related Protein ELISA Kit | MyBioSource MBS043423 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Haptoglobin Related Protein ELISA Kit

catalog :

MBS043423

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS043423

products type :

ELISA Kit

products full name :

Human Haptoglobin Related Protein ELISA Kit

products short name :

Haptoglobin Related Protein

other names :

haptoglobin-related protein; Haptoglobin-related protein; haptoglobin-related protein; Haptoglobin-related locus; haptoglobin-related protein

products gene name :

HPR

other gene names :

HPR; HPR; HP; A-259H10.2

uniprot entry name :

HPTR_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between Human HPR and analogues was observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma, Tissue Homogenate, Feces and Urine. Assay Type: Sandwich. Detection Range: 3.12ng/ml-100ng/ml. Sensitivity: 1.0ng/ml.

other info2 :

Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated HPR concentrations in Human serum, plasma and other body fluids. Using Purified Human HPR antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add HPR and HPR antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of HPR in the samples is then determined by comparing the O.D. of the samples to the standard curve. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated HPR concentrations in Human serum, plasma and other body fluids. Using Purified Human HPR antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add HPR and HPR antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of HPR in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

45580723

ncbi acc num :

NP_066275.3

ncbi gb acc num :

NM_020995.3

uniprot acc num :

P00739

ncbi mol weight :

39,030 Da

ncbi pathways :

African Trypanosomiasis Pathway (194384); African Trypanosomiasis Pathway (194323); Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); Scavenging Of Heme From Plasma Pathway (771600)

ncbi summary :

This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]

uniprot summary :

HPR: a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 16q22.1. Cellular Component: extracellular region. Molecular Function: hemoglobin binding; catalytic activity. Biological Process: receptor-mediated endocytosis; metabolic process

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage