catalog number :
MBS043226
products type :
ELISA Kit
products full name :
Bovine Placental Lactogen ELISA Kit
products short name :
[Placental Lactogen]
other names :
[placental lactogen; Chorionic somatomammotropin hormone; chorionic somatomammotropin hormone; choriomammotropin; placental lactogen; chorionic somatomammotropin A; chorionic somatomammotropin hormone 1 (placental lactogen); Lactogen; Placental lactogen]
products gene name :
[PL]
other gene names :
[CSH1; CSH1; PL; CSA; CS-1; CSMT; hCS-A; Choriomammotropin; PL]
uniprot entry name :
CSH_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Bovine body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich. Detection Range: 15.6 nmol/L - 500 nmol/L. Sensitivity: 2.0 nmol/L.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PL (hereafter termed "analyte") in undiluted original Bovine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
AAA98621.1
ncbi mol weight :
25,020 Da
ncbi pathways :
Cytokine Signaling In Immune System Pathway (366171); Growth Hormone Receptor Signaling Pathway (477128); Immune System Pathway (106386); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Nuclear Signaling By ERBB4 Pathway (530744); PI3K-Akt Signaling Pathway (692234); PI3K-Akt Signaling Pathway (692979)
ncbi summary :
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008]
uniprot summary :
CSH1: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. Belongs to the somatotropin/prolactin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 17q24.2. Cellular Component: extracellular region. Molecular Function: metal ion binding; hormone activity
size4 :
10x96-Strip-Wells