Porcine Dna Damage Inducible Transcript 3 ELISA Kit | MyBioSource MBS042690 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Porcine Dna Damage Inducible Transcript 3 ELISA Kit

catalog :

MBS042690

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS042690

products type :

ELISA Kit

products full name :

Porcine Dna Damage Inducible Transcript 3 ELISA Kit

products short name :

[Dna Damage Inducible Transcript 3]

other names :

[DNA damage-inducible transcript 3 protein isoform 2; DNA damage-inducible transcript 3 protein; DNA damage-inducible transcript 3 protein; DDIT-3; C/EBP zeta; c/EBP-homologous protein 10; CCAAT/enhancer-binding protein homologous protein; growth arrest and DNA damage-inducible protein GADD153; DNA-damage-inducible transcript 3; C/EBP zeta; C/EBP-homologous protein; CHOP; C/EBP-homologous protein 10; CHOP-10; CCAAT/enhancer-binding protein homologous protein; Growth arrest and DNA damage-inducible protein GADD153]

products gene name :

[DDIT3]

other gene names :

[DDIT3; DDIT3; CHOP; CEBPZ; CHOP10; CHOP-10; GADD153; CHOP; CHOP10; GADD153; DDIT-3; CHOP; CHOP-10]

uniprot entry name :

DDIT3_HUMAN

reactivity :

Porcine

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma and Tissue Homogenate. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml. Assay Type: Sandwich

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of DDIT3 (hereafter termed this analyte) in undiluted original Porcine serum, plasma and tissue homogenate samples.

ncbi gi num :

304282234

ncbi acc num :

NP_001181986.1

ncbi gb acc num :

NM_001195057.1

uniprot acc num :

P35638

ncbi mol weight :

19,175 Da

ncbi pathways :

ATF-2 Transcription Factor Network Pathway (138006); Activation Of Chaperone Genes By ATF6-alpha Pathway (530770); Activation Of Chaperones By ATF6-alpha Pathway (105905); Activation Of Genes By ATF4 Pathway (530772); Adipogenesis Pathway (198832); MAPK Signaling Pathway (198779); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Metabolism Of Proteins Pathway (106230); PERK Regulated Gene Expression Pathway (105907)

ncbi summary :

This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]

uniprot summary :

CHOP: a transcriptional-regulatory protein of the bZIP family. Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA. May play an important role in melanoma progression. CK2-mediated phosphorylation inhibits its transcriptional activity. Up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform. Protein type: Autophagy; DNA-binding; Transcription factor; Oncoprotein. Chromosomal Location of Human Ortholog: 12q13.1-q13.2. Cellular Component: nucleoplasm; late endosome; cytosol; nucleus. Molecular Function: leucine zipper domain binding; protein binding; DNA binding; protein heterodimerization activity; transcription corepressor activity; transcription factor binding; transcription factor activity. Biological Process: regulation of transcription in response to stress; proteasomal ubiquitin-dependent protein catabolic process; Wnt receptor signaling pathway; negative regulation of protein kinase B signaling cascade; unfolded protein response; negative regulation of transcription factor activity; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; mRNA transcription from RNA polymerase II promoter; blood vessel maturation; response to unfolded protein; response to starvation; positive regulation of interleukin-8 production; cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; regulation of transcription, DNA-dependent; cell redox homeostasis; release of sequestered calcium ion into cytosol; positive regulation of neuron apoptosis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of myoblast differentiation; inhibition of CREB transcription factor; cell cycle arrest; negative regulation of transcription, DNA-dependent; response to DNA damage stimulus; ER overload response. Disease: Myxoid Liposarcoma

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095