catalog number :
MBS042653
products type :
ELISA Kit
products full name :
Rat Phospholipid Scramblase 1 ELISA Kit
products short name :
Phospholipid Scramblase 1
other names :
phospholipid scramblase 1; Phospholipid scramblase 1; phospholipid scramblase 1; PL scramblase 1; erythrocyte phospholipid scramblase; ca(2+)-dependent phospholipid scramblase 1; phospholipid scramblase 1; Ca(2+)-dependent phospholipid scramblase 1; Erythrocyte phospholipid scramblase; MmTRA1b
products gene name :
PLSCR1
other gene names :
PLSCR1; PLSCR1; MMTRA1B; PL scramblase 1
uniprot entry name :
PLS1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PLSCR1 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_066928.1
ncbi gb acc num :
NM_021105.2
ncbi mol weight :
35,049 Da
ncbi pathways :
EGFR1 Signaling Pathway (198782)
uniprot summary :
PLSCR1: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Belongs to the phospholipid scramblase family. Protein type: Membrane protein, integral; Calcium-binding. Chromosomal Location of Human Ortholog: 3q23. Cellular Component: extracellular matrix; Golgi apparatus; membrane; integral to plasma membrane; plasma membrane; nucleolus; cytosol; nucleus; lipid raft. Molecular Function: phospholipid scramblase activity; protein binding; enzyme binding; DNA binding; calcium ion binding; SH3 domain binding; CD4 receptor binding; epidermal growth factor receptor binding. Biological Process: platelet activation; negative regulation of viral genome replication; apoptosis; positive regulation of innate immune response; acute-phase response; positive regulation of transcription from RNA polymerase II promoter; phospholipid scrambling; defense response to virus; regulation of mast cell activation; phosphatidylserine biosynthetic process