catalog number :
MBS042633
products type :
ELISA Kit
products full name :
Human Pepsin ELISA Kit
products short name :
[Pepsin]
other names :
[pepsin A-5 preproprotein; Pepsin A-5; pepsin A-5; pepsinogen-5; pepsinogen A5; pepsinogen 5, group I (pepsinogen A); Pepsinogen-5]
products gene name :
[PP]
other gene names :
[PGA5; PGA5]
uniprot entry name :
PEPA5_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Mouse Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of POT1 (hereafter termed "analyte") in undiluted original Mouse body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_055039.1
ncbi gb acc num :
NM_014224.3
ncbi mol weight :
41,993 Da
ncbi pathways :
Protein Digestion And Absorption Pathway (172847); Protein Digestion And Absorption Pathway (171868)
ncbi summary :
This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. [provided by RefSeq, Jul 2015]
uniprot summary :
PGA5: Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. Belongs to the peptidase A1 family. Protein type: Secreted; EC 3.4.23.1; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 11q13. Molecular Function: aspartic-type endopeptidase activity. Biological Process: digestion; proteolysis
size4 :
10x96-Strip-Wells