catalog number :
MBS042471
products type :
ELISA Kit
products full name :
Rabbit Total Prostaglandin ELISA Kit
products short name :
Total Prostaglandin
other names :
T-cell leukemia homeobox protein 2; T-cell leukemia homeobox protein 2; T-cell leukemia homeobox protein 2; homeo box 11-like 1; homeobox protein Hox-11L1; neural crest homeobox protein; T-cell leukemia homeobox 2; Homeobox protein Hox-11L1; Neural crest homeobox protein
other gene names :
TLX2; TLX2; NCX; HOX11L1; HOX11L1; NCX
uniprot entry name :
TLX2_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich
ncbi mol weight :
30,251 Da
ncbi pathways :
ALK1 Signaling Events Pathway (137968); ALK2 Signaling Events Pathway (137983); Neural Crest Differentiation Pathway (672460)
ncbi summary :
This gene is a member of an orphan homeobox-containing transcription factor family. Studies of the mouse ortholog have shown that the encoded protein is crucial for the development of the enteric nervous system; in humans, loss-of-function may play a role in tumorigenesis of gastrointestinal stromal tumors. [provided by RefSeq, May 2010]
uniprot summary :
TLX2: Transcription activator that binds DNA elements with the consensus sequence 5 -CGGTAATTGG-3 . Binds DNA via its homeobox. Required for normal cell death of enteric neurons in the gastrointestinal tract. Required for normal development of the enteric nervous system, and for proper development of normal motility of the gastrointestinal tract. Protein type: Cell development/differentiation; Transcription factor; DNA-binding. Chromosomal Location of Human Ortholog: 2p13.1. Cellular Component: cytoplasm; nucleus. Molecular Function: sequence-specific DNA binding. Biological Process: regulation of transcription, DNA-dependent; mesoderm formation; transcription, DNA-dependent; negative regulation of dendrite morphogenesis; enteric nervous system development