Human Sex Hormone Binding Globulin ELISA Kit | MyBioSource MBS042054 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Sex Hormone Binding Globulin ELISA Kit

catalog :

MBS042054

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS042054

products type :

ELISA Kit

products full name :

Human Sex Hormone Binding Globulin ELISA Kit

products short name :

Sex Hormone Binding Globulin

other names :

sex hormone-binding globulin isoform 1; Sex hormone-binding globulin; sex hormone-binding globulin; sex steroid-binding protein; testosterone-binding beta-globulin; testosterone-estrogen-binding globulin; testosterone-estradiol-binding globulin; testis-specific androgen-binding protein; sex hormone-binding globulin; Sex steroid-binding protein; SBP; Testis-specific androgen-binding protein; ABP; Testosterone-estradiol-binding globulin; TeBG; Testosterone-estrogen-binding globulin

products gene name :

SHBG

other gene names :

SHBG; SHBG; ABP; SBP; TEBG; SHBG; SBP; ABP; TeBG

uniprot entry name :

SHBG_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between Human SHBG and analogues was observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Assay Type: Sandwich. Detection Range: 6.25 nmol/L - 200 nmol/L. Sensitivity: 1.0 nmol/L.

other info2 :

Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated SHBG concentrations in Human serum, plasma and other body fluids. Using Purified Human SHBG antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add SHBG and SHBG antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of SHBG in the samples is then determined by comparing the O.D. of the samples to the standard curve. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean x100]

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated SHBG concentrations in Human serum, plasma and other body fluids. Using Purified Human SHBG antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add SHBG and SHBG antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of SHBG in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

7382460

ncbi acc num :

NP_001031.2

ncbi gb acc num :

NM_001040.3

uniprot acc num :

P04278

ncbi mol weight :

43,779 Da

ncbi pathways :

Nongenotropic Androgen Signaling Pathway (138048)

ncbi summary :

This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein binds each steroid molecule as a dimer formed from identical or nearly identical monomers. The use of alternate promoters and alternatively spliced transcripts have been described. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

uniprot summary :

SHBG: Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 17p13.1. Cellular Component: extracellular region. Molecular Function: androgen binding. Biological Process: primary spermatocyte growth

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage