ELISA/assay

Hamster Cathepsin D ELISA Kit

MBS041690

48-Strip-Wells

435 USD

ELISA Kit

Hamster Cathepsin D ELISA Kit

Cathepsin D

CTSD; Cathepsin D; cathepsin D; lysosomal aspartyl protease; lysosomal aspartyl peptidase; ceroid-lipofuscinosis, neuronal 10; cathepsin D

CTSD

CTSD; CTSD; CPSD; CLN10; CPSD

CATD_HUMAN

Hamster

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Undiluted original Hamster body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 15.6 pg/ml - 500 pg/ml. Sensitivity: 2.0 pg/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CTSD (hereafter termed "analyte") in undiluted original Hamster body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

48146011

CAG33228.1

P07339

44,552 Da

Adaptive Immune System Pathway (366160); Ceramide Signaling Pathway (138023); Degradation Of Collagen Pathway (730309); Degradation Of The Extracellular Matrix Pathway (576263); Direct P53 Effectors Pathway (137939); Extracellular Matrix Organization Pathway (576262); Immune System Pathway (106386); LKB1 Signaling Events Pathway (137957); Lysosome Pathway (99052); Lysosome Pathway (96865)

This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq, Jul 2008]

CTSD: Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. Consists of a light chain and a heavy chain. Belongs to the peptidase A1 family. Protein type: Protease; EC 3.4.23.5; Autophagy; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 11p15.5. Cellular Component: extracellular matrix; lysosomal lumen; extracellular space; lysosome; melanosome; extracellular region. Molecular Function: protein binding; aspartic-type endopeptidase activity. Biological Process: collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; antigen processing and presentation of exogenous peptide antigen via MHC class II; proteolysis. Disease: Ceroid Lipofuscinosis, Neuronal, 10

48-Strip-Wells

435 USD

96-Strip-Wells

600