catalog number :
MBS041065
products type :
ELISA Kit
products full name :
Human Interleukin 11 ELISA Kit
products short name :
[Interleukin 11]
other names :
[interleukin-11 isoform 2; Interleukin-11; interleukin-11; oprelvekin; adipogenesis inhibitory factor; interleukin 11; Adipogenesis inhibitory factor]
products gene name :
[IL-11]
other gene names :
[IL11; IL11; AGIF; IL-11; IL-11; AGIF]
uniprot entry name :
IL11_HUMAN
storage stability :
Store all reagents at 2-8 degree C
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Rat Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 31.2pg/ml-1000pg/ml. Sensitivity: 5.0pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%)is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of IL10RB (hereafter termed "analyte") in undiluted original Rat body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001254647.1
ncbi gb acc num :
NM_001267718.1
ncbi mol weight :
21,429 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Integrated Pancreatic Cancer Pathway (711360); Interleukin-11 Signaling Pathway (698753); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Rheumatoid Arthritis Pathway (200309); Rheumatoid Arthritis Pathway (200269)
ncbi summary :
The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
uniprot summary :
IL11: Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Belongs to the IL-6 superfamily. Protein type: Motility/polarity/chemotaxis; Cell cycle regulation; Cytokine; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 19q13.3-q13.4. Cellular Component: extracellular space; cytoplasm; extracellular region. Molecular Function: growth factor activity; cytokine activity; interleukin-11 receptor binding. Biological Process: fat cell differentiation; positive regulation of peptidyl-tyrosine phosphorylation; cell-cell signaling; positive regulation of MAPKKK cascade; megakaryocyte differentiation; B cell differentiation; negative regulation of hormone secretion; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of peptidyl-serine phosphorylation
size4 :
10x96-Strip-Wells