catalog number :
MBS040798
products type :
ELISA Kit
products full name :
Human Glypican 4 ELISA Kit
products short name :
Glypican 4
other names :
glypican-4; Glypican-4; glypican-4; dJ900E8.1 (glypican 4); glypican proteoglycan 4; glypican 4; K-glypican
products gene name :
GPC4
other gene names :
GPC4; GPC4; K-glypican
uniprot entry name :
GPC4_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Detection Range: The detection range of this kit is 62.5pg/ml-2000pg/ml.
other info2 :
Sensitivity: The sensitivity of this kit is 10pg/ml. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GPC4 (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_001439.2
ncbi gb acc num :
NM_001448.2
ncbi mol weight :
62,412 Da
ncbi pathways :
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway 645305!!Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway 645308!!Disease Pathway 530764!!Diseases Associated With Visual Transduction Pathway 771581!!Glycosaminoglycan Metabolism Pathway 645297!!HS-GAG Biosynthesis Pathway 645306!!HS-GAG Degradation Pathway 645307!!Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway 645304!!MPS I - Hurler Syndrome Pathway 685537!!MPS II - Hunter Syndrome Pathway 685538
ncbi summary :
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system . By similarity. Subcellular location: Cell membrane; Lipid-anchor GPI-anchor; Extracellular side . By similarity. Secreted glypican-4: Secreted extracellular space . By similarity. Sequence similarities: Belongs to the glypican family.