catalog number :
MBS040608
products type :
ELISA Kit
products full name :
Human Pyridoxal /Pyridoxine Vitamin B6 Kinase ELISA Kit
products short name :
[Pyridoxal /Pyridoxine Vitamin B6 Kinase]
other names :
[PDXK protein; Pyridoxal kinase; pyridoxal kinase; pyridoxine kinase; vitamin B6 kinase; pyridoxamine kinase; pyridoxal (pyridoxine, vitamin B6) kinase; Pyridoxine kinase]
products gene name :
[PDXK]
other gene names :
[PDXK; PDXK; PKH; PNK; PRED79; C21orf97; C21orf124; C21orf124; C21orf97; PKH; PNK]
uniprot entry name :
PDXK_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Canine Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.25ng/ml-8ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%)is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of PDPN (hereafter termed "analyte") in undiluted original Canine body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
AAH05825.1
ncbi mol weight :
35,102 Da
ncbi pathways :
Metabolism Pathway (477135); Metabolism Of Vitamins And Cofactors Pathway (106249); Metabolism Of Water-soluble Vitamins And Cofactors Pathway (106250); Vitamin B6 Metabolism Pathway (83013); Vitamin B6 Metabolism Pathway (399); Vitamins B6 Activation To Pyridoxal Phosphate Pathway (187206); Pyridoxal 5'-phosphate Salvage Pathway (142237)
ncbi summary :
The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
uniprot summary :
PDXK: Required for synthesis of pyridoxal-5-phosphate from vitamin B6. Belongs to the pyridoxine kinase family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Kinase, other; Cofactor and Vitamin Metabolism - vitamin B6; EC 2.7.1.35. Chromosomal Location of Human Ortholog: 21q22.3. Cellular Component: nucleoplasm; cytoplasm; cytosol; nucleus. Molecular Function: potassium ion binding; sodium ion binding; protein homodimerization activity; zinc ion binding; pyridoxal kinase activity; magnesium ion binding; lithium ion binding; ATP binding; pyridoxal phosphate binding. Biological Process: cell proliferation; vitamin B6 metabolic process; vitamin metabolic process; pyridoxal 5 -phosphate salvage; phosphorylation; water-soluble vitamin metabolic process; pyridoxal phosphate biosynthetic process
size4 :
10x96-Strip-Wells