ELISA/assay

Sheep Pulmonary Surfactant Associated Protein C ELISA Kit

MBS040491

48-Strip-Wells

435 USD

ELISA Kit

Sheep Pulmonary Surfactant Associated Protein C ELISA Kit

Pulmonary Surfactant Associated Protein C

pulmonary surfactant-associated protein C; Pulmonary surfactant-associated protein C; pulmonary surfactant-associated protein C; pulmonary surfactant-associated proteolipid SPL(Val); surfactant associated protein C; Pulmonary surfactant-associated proteolipid SPL(Val); SP5

SPC

Sftpc; Sftpc; SP5; SPC; SP-C; Sftp2; Bricd6; Sftp-2; pro-SpC; Sftp2; SP-C

PSPC_MOUSE

Sheep

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Undiluted original Sheep body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 3.12 pg/ml - 100 pg/ml. Sensitivity: 1.0 pg/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SPC (hereafter termed "analyte") in undiluted original Sheep body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

256355065

NP_035489.2

NM_011359.2

P21841

21,055 Da

SFTPC: Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. Defects in SFTPC are the cause of pulmonary surfactant metabolism dysfunction type 2 (SMDP2); also called pulmonary alveolar proteinosis due to surfactant protein C deficiency. A rare disease associated with progressive respiratory insufficiency and lung disease with a variable clinical course, due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. Genetic variations in SFTPC are a cause of susceptibility to respiratory distress syndrome in premature infants (RDS); also known as RDS in prematurity. RDS is a lung disease affecting usually premature newborn infants. It is characterized by deficient gas exchange, diffuse atelectasis, high-permeability lung edema and fibrin-rich alveolar deposits called hyaline membranes . 2 isoforms of the human protein are produced by alternative splicing. Protein type: Lipid-binding. Cellular Component: multivesicular body; extracellular space; cytoplasm; extracellular region. Molecular Function: protein homodimerization activity. Biological Process: protein homooligomerization

48-Strip-Wells

435 USD

96-Strip-Wells

600