This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse Thyroglobulin ELISA Kit
catalog :
MBS039215
quantity :
48-Strip-Wells
price :
470 USD
product information
catalog number :
MBS039215
products type :
ELISA Kit
products full name :
Mouse Thyroglobulin ELISA Kit
products short name :
[Thyroglobulin]
other names :
[thyroglobulin; Thyroglobulin; thyroglobulin; thyroglobulin]
products gene name :
[TG]
other gene names :
[TG; TG; TGN; AITD3; Tg]
uniprot entry name :
THYG_HUMAN
reactivity :
Mouse
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.25ng/ml-8ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of TFF1 (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
55770862
ncbi acc num :
NP_003226.4
ncbi gb acc num :
NM_003235.4
uniprot acc num :
P01266
ncbi mol weight :
304,790 Da
ncbi pathways :
Autoimmune Thyroid Disease Pathway (83121); Autoimmune Thyroid Disease Pathway (533); Thyroid Hormone Synthesis Pathway (835410); Thyroid Hormone Synthesis Pathway (839541)
ncbi summary :
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
uniprot summary :
TG: Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Defects in TG are the cause of thyroid dyshormonogenesis 3 (TDH3). A disorder due to thyroid dyshormonogenesis, causing large goiters of elastic and soft consistency in the majority of patients. Although the degree of thyroid dysfunction varies considerably among patients with defective thyroglobulin synthesis, patients usually have a relatively high serum free triiodothyronine (T3) concentration with disproportionately low free tetraiodothyronine (T4) level. The maintenance of relatively high free T3 levels prevents profound tissue hypothyroidism except in brain and pituitary, which are dependent on T4 supply, resulting in neurologic and intellectual defects in some cases. Variations in TG are associated with susceptibility to autoimmune thyroid disease type 3 (AITD3). AITDs including Graves disease (GD) and Hashimoto thyroiditis (HT), are among the most common human autoimmune diseases. They are complex diseases, which are caused by an interaction between susceptibility genes and nongenetic factors, such as infection. Belongs to the type-B carboxylesterase/lipase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 8q24. Cellular Component: extracellular space; extracellular region. Molecular Function: hormone activity. Biological Process: regulation of myelination; iodide transport; thyroid gland development; hormone biosynthetic process; signal transduction; thyroid hormone metabolic process. Disease: Thyroid Dyshormonogenesis 3; Autoimmune Thyroid Disease, Susceptibility To, 3
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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