ELISA/assay

Hamster Lipoprotein A ELISA Kit

MBS038903

48-Strip-Wells

435 USD

ELISA Kit

Hamster Lipoprotein A ELISA Kit

Lipoprotein A

lipoprotein, Lp(a); Apolipoprotein(a); apolipoprotein(a); apolipoprotein(a); lp(a); apo(a); antiangiogenic AK38 protein; lipoprotein, Lp(a)

LP-A

LPA; LPA; LP; AK38; APOA; Apo(a); Lp(a)

APOA_HUMAN

Hamster

No significant cross-reactivity or interference between Hamster LP-A and analogues was observed.

Store all reagents at 2-8 degree C

Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Assay Type: Sandwich. Detection Range: 25 ?g/ml - 800 ?g/ml. Sensitivity: 2.0 ?g/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean x100]

Introduction: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate LP-A concentrations in Hamster serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications!

119567981

EAW47596.1

P08519

501,319 Da

LDL-mediated Lipid Transport Pathway (106159); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Amb2 Integrin Signaling Pathway (137945)

The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence. [provided by RefSeq, Dec 2009]

LPA: Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330. Belongs to the peptidase S1 family. Plasminogen subfamily. Protein type: EC 3.4.21.-; Inhibitor; Protease. Chromosomal Location of Human Ortholog: 6q26. Cellular Component: extracellular region. Molecular Function: heparin binding; protein binding; serine-type endopeptidase activity; fibronectin binding; endopeptidase inhibitor activity; apolipoprotein binding. Biological Process: receptor-mediated endocytosis; blood circulation; lipoprotein metabolic process; lipid metabolic process; lipid transport; proteolysis

48-Strip-Wells

435 USD

96-Strip-Wells

600