Human Phosphorylated Alpha Synuclein ELISA Kit | MyBioSource MBS038716 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Phosphorylated Alpha Synuclein ELISA Kit

catalog :

MBS038716

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS038716

products type :

ELISA Kit

products full name :

Human Phosphorylated Alpha Synuclein ELISA Kit

products short name :

Phosphorylated Alpha Synuclein

other names :

alpha-synuclein; Alpha-synuclein; alpha-synuclein; alpha SYN; non-A4 component of amyloid; non-A beta component of AD amyloid; synuclein, alpha; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor

products gene name :

PSNCA

other gene names :

Snca; Snca; NACP; alphaSYN; Syn; NACP

uniprot entry name :

SYUA_MOUSE

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PSNCA (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

109638747

ncbi acc num :

NP_001035916.1

ncbi gb acc num :

NM_001042451.1

uniprot acc num :

O55042

ncbi mol weight :

14,485 Da

ncbi pathways :

Alzheimer's Disease Pathway (83294); Alzheimer's Disease Pathway (509); Amyloids Pathway (819491); Disease Pathway (819462); EGFR1 Signaling Pathway (198278); Parkinson's Disease Pathway (83295)

uniprot summary :

SNCA: a member of the synuclein family. Abundantly expressed in the brain. Inhibits phospholipase D2 selectively. May integrate presynaptic signaling and membrane trafficking. Implicated in the pathogenesis of Parkinson s disease. A major component of amyloid plaques in the brains of patients with Alzheimer s disease. Two alternatively spliced isoforms transcripts have been identified. Protein type: Adaptor/scaffold. Cellular Component: Golgi apparatus; nuclear outer membrane; mitochondrion; terminal button; inclusion body; cytosol; synaptic vesicle; platelet alpha granule membrane; perinuclear region of cytoplasm; cytoplasm; synapse; cytoplasmic vesicle membrane; rough endoplasmic reticulum; intracellular membrane-bound organelle; cell; fibril; cell cortex; actin cytoskeleton; growth cone; cytoskeleton; axon; plasma membrane; ribosome; nerve terminal; nucleus. Molecular Function: identical protein binding; zinc ion binding; histone binding; kinesin binding; ferrous iron binding; metal ion binding; magnesium ion binding; oxidoreductase activity; Hsp70 protein binding; calcium ion binding; enzyme binding; phospholipase binding; phospholipid binding; alpha-tubulin binding; protein domain specific binding; microtubule binding; caspase inhibitor activity; beta-tubulin binding; phosphoprotein binding; protein N-terminus binding; arachidonic acid binding; dynein binding; protein binding; copper ion binding; tau protein binding. Biological Process: regulation of acyl-CoA biosynthetic process; adult locomotory behavior; regulation of neurotransmitter secretion; positive regulation of endocytosis; response to lipopolysaccharide; dopamine biosynthetic process; dopamine metabolic process; positive regulation of neurotransmitter secretion; response to magnesium ion; regulation of neuron apoptosis; synapse organization and biogenesis; negative regulation of neuron apoptosis; response to drug; negative regulation of dopamine metabolic process; synaptic vesicle endocytosis; negative regulation of transporter activity; negative regulation of apoptosis; regulation of neuronal synaptic plasticity; regulation of long-term neuronal synaptic plasticity; negative regulation of serotonin uptake; synaptic transmission, dopaminergic; negative regulation of norepinephrine uptake; mitochondrial membrane organization and biogenesis; microglial cell activation; negative regulation of monooxygenase activity; negative regulation of caspase activity; fatty acid metabolic process; regulation of dopamine secretion; positive regulation of synaptic transmission; negative regulation of histone acetylation; negative regulation of dopamine uptake; synaptic transmission; negative regulation of exocytosis; negative regulation of protein amino acid phosphorylation; behavioral response to cocaine; receptor internalization; phospholipid metabolic process; response to iron(II) ion; positive regulation of receptor recycling; caspase activation; neutral lipid metabolic process; protein destabilization; negative regulation of microtubule polymerization; regulation of glutamate secretion; regulation of macrophage activation; synaptic vesicle transport; positive regulation of peptidyl-serine phosphorylation; organelle ATP synthesis coupled electron transport; regulation of locomotion; positive regulation of release of sequestered calcium ion into cytosol; regulation of excitatory postsynaptic membrane potential

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage