Human Aldose Reductase ELISA Kit | MyBioSource MBS036989 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Aldose Reductase ELISA Kit

catalog :

MBS036989

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS036989

products type :

ELISA Kit

products full name :

Human Aldose Reductase ELISA Kit

products short name :

Aldose Reductase

other names :

aldose reductase; Aldose reductase; aldose reductase; aldehyde reductase 1; low Km aldose reductase; Lii5-2 CTCL tumor antigen; aldo-keto reductase family 1 member B1; aldo-keto reductase family 1, member B1 (aldose reductase); Aldehyde reductase; Aldo-keto reductase family 1 member B1

products gene name :

other gene names :

AKR1B1; AKR1B1; AR; ADR; ALR2; ALDR1; ALDR1; AR

uniprot entry name :

ALDR_HUMAN

reactivity :

Human

specificity :

This kit recognizes recombinant and natural Human AR, no significant cross-reactivity or interference was observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Detection Range: 3.12 U/L ~ 100 U/L. Sensitivity: 1.0 U/L.

other info2 :

Intended Uses: This ELISA kit is intended for laboratory in vitro research use only, not for drug, household or other use! The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm by a spectrophotometer. In order to measure the concentration of Human AR in the sample, this ELISA kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versus Human AR concentration. The concentration of Human AR in the samples is then determined by comparing the O.D. of the samples to the standard curve. Intra-assay Precision: Intra-assay CV (%) are less than 15%. Inter-assay Precision: Inter-assay CV (%) are less than 15%.

products description :

Introduction: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample.

ncbi gi num :

4502049

ncbi acc num :

NP_001619.1

ncbi gb acc num :

NM_001628.2

uniprot acc num :

P15121

ncbi mol weight :

35,853 Da

ncbi pathways :

Fructose And Mannose Metabolism Pathway (82930); Fructose And Mannose Metabolism Pathway (291); Galactose Metabolism Pathway (82931); Galactose Metabolism Pathway (292); Glycerolipid Metabolism Pathway (82986); Glycerolipid Metabolism Pathway (361); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Metabolism Of Steroid Hormones And Vitamin D Pathway (106150); Pentose And Glucuronate Interconversions Pathway (82929)

ncbi summary :

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]

uniprot summary :

AKR1B1: Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. Belongs to the aldo/keto reductase family. Protein type: Carbohydrate Metabolism - pentose and glucuronate interconversions; EC 1.1.1.21; Carbohydrate Metabolism - pyruvate; Lipid Metabolism - glycerolipid; Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - galactose; Oxidoreductase. Chromosomal Location of Human Ortholog: 7q35. Cellular Component: nucleoplasm; extracellular space; cytoplasm; cytosol. Molecular Function: glyceraldehyde oxidoreductase activity; electron carrier activity; aldo-keto reductase activity; aldehyde reductase activity. Biological Process: steroid metabolic process; carbohydrate metabolic process; C21-steroid hormone biosynthetic process; response to stress

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage