ELISA/assay

Rat Trypsinogen Activation Peptide ELISA Kit

MBS036758

48-Strip-Wells

435 USD

ELISA Kit

Rat Trypsinogen Activation Peptide ELISA Kit

Trypsinogen Activation Peptide

Trypsin-1; Trypsin-1; trypsin-1; beta-trypsin; trypsinogen 1; trypsinogen A; digestive zymogen; cationic trypsinogen; nonfunctional trypsin 1; protease, serine, 1 (trypsin 1); Beta-trypsin; Cationic trypsinogen; Serine protease 1; Trypsin I

TAP

PRSS1; PRSS1; TRP1; TRY1; TRY4; TRYP1; TRP1; TRY1; TRYP1

TRY1_HUMAN

Rat

247

Store all reagents at 2-8 degree C

Assay Type: Sandwich

136408

P07477.1

P07477

26,558 Da

Activation Of Matrix Metalloproteinases Pathway (576264); Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway (833804); Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway (906000); Defective BTD Causes Biotidinase Deficiency Pathway (906015); Defective CD320 Causes Methylmalonic Aciduria Pathway (906012); Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway (906001); Defective GIF Causes Intrinsic Factor Deficiency Pathway (906004); Defective HLCS Causes Multiple Carboxylase Deficiency Pathway (906014); Defective LMBRD1 Causes Methylmalonic Aciduria And Homocystinuria Type CblF Pathway (906003); Defective MMAA Causes Methylmalonic Aciduria Type CblA Pathway (906010)

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq, Jul 2008]

trypsin 1: Has activity against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec. The single-chain form is more active than the two- chain form against all of these substrates. Defects in PRSS1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Belongs to the peptidase S1 family. Protein type: Protease; Secreted, signal peptide; Secreted; EC 3.4.21.4. Chromosomal Location of Human Ortholog: 7q34. Cellular Component: extracellular region. Molecular Function: metal ion binding; serine-type endopeptidase activity. Biological Process: extracellular matrix disassembly; extracellular matrix organization and biogenesis; vitamin metabolic process; cobalamin metabolic process; digestion; proteolysis; water-soluble vitamin metabolic process. Disease: Trypsinogen Deficiency; Pancreatitis, Hereditary

48-Strip-Wells

435 USD

96-Strip-Wells

600