catalog number :
MBS036638
products type :
ELISA Kit
products full name :
Goat Vitamin D Binding Protein ELISA Kit
products short name :
Vitamin D Binding Protein
other names :
vitamin D-binding protein isoform 3; Vitamin D-binding protein; vitamin D-binding protein; VDB; gc-globulin; vitamin D-binding alpha-globulin; group-specific component (vitamin D binding protein); Gc-globulin; Group-specific component
other gene names :
GC; GC; DBP; GRD3; VDBG; VDBP; DBP/GC; DBP; VDB
uniprot entry name :
VTDB_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich
ncbi acc num :
NP_001191236.1
ncbi gb acc num :
NM_001204307.1
ncbi mol weight :
52,964 Da
ncbi pathways :
Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Metabolism Of Steroid Hormones And Vitamin D Pathway (106150); Vitamin D (calciferol) Metabolism Pathway (160956); Vitamin D Synthesis Pathway (198764)
ncbi summary :
The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
uniprot summary :
GC: Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 4q12-q13. Cellular Component: extracellular space; lysosomal lumen; extracellular region; cytosol. Molecular Function: vitamin D binding; actin binding; vitamin transporter activity. Biological Process: steroid metabolic process; vitamin transport; vitamin D metabolic process. Disease: Graves Disease, Susceptibility To, 1