catalog number :
MBS036280
products type :
ELISA Kit
products full name :
Canine Hemopexin ELISA Kit
products short name :
[Hemopexin]
other names :
[hemopexin; Hemopexin; hemopexin; beta-1B-glycoprotein; hemopexin; Beta-1B-glycoprotein]
products gene name :
[HPX]
other gene names :
[HPX; HPX; HX]
uniprot entry name :
HEMO_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 62.5 ng/ml - 2000 ng/ml. Sensitivity: 10 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HPX (hereafter termed this analyte) in undiluted original Canine serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_000604.1
ncbi gb acc num :
NM_000613.2
ncbi mol weight :
51,676 Da
ncbi pathways :
Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); Scavenging Of Heme From Plasma Pathway (771600)
ncbi summary :
This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress. [provided by RefSeq, Apr 2009]
uniprot summary :
HPX: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Belongs to the hemopexin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 11p15.5-p15.4. Cellular Component: extracellular space; extracellular region. Molecular Function: protein binding; metal ion binding; heme transporter activity. Biological Process: receptor-mediated endocytosis; positive regulation of humoral immune response mediated by circulating immunoglobulin; positive regulation of immunoglobulin production; heme transport; positive regulation of tyrosine phosphorylation of Stat1 protein; viral reproduction; cellular iron ion homeostasis; hemoglobin metabolic process; heme metabolic process
size4 :
10x96-Strip-Wells