Mouse Low-Density Lipoprotein Receptor-Related Protein 1 ELISA Kit | MyBioSource MBS035811 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Low-Density Lipoprotein Receptor-Related Protein 1 ELISA Kit

catalog :

MBS035811

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS035811

products type :

ELISA Kit

products full name :

Mouse Low-Density Lipoprotein Receptor-Related Protein 1 ELISA Kit

products short name :

[Low-Density Lipoprotein Receptor-Related Protein 1]

other names :

[LRP1 protein; Prolow-density lipoprotein receptor-related protein 1; prolow-density lipoprotein receptor-related protein 1; LRP-1; type V tgf-beta receptor; apolipoprotein E receptor; alpha-2-macroglobulin receptor; TbetaR-V/LRP-1/IGFBP-3 receptor; low density lipoprotein receptor-related protein 1; Alpha-2-macroglobulin receptor; A2MR; Apolipoprotein E receptor]

products gene name :

[LRP1]

other gene names :

[LRP1; LRP1; APR; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R; A2MR; APR; LRP-1; A2MR; APOER; LRP-85; LRP-515; LRPICD]

uniprot entry name :

LRP1_HUMAN

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Human Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of LRIG2 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

ncbi gi num :

47940659

ncbi acc num :

AAH72015.1

uniprot acc num :

Q07954

ncbi mol weight :

504,606 Da

ncbi pathways :

Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); Disease Pathway (530764); Diseases Associated With Visual Transduction Pathway (771581); Malaria Pathway (152665); Malaria Pathway (152657); PDGFR-beta Signaling Pathway (138071); Retinoid Metabolism And Transport Pathway (187208)

ncbi summary :

The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. [provided by RefSeq, Jan 2010]

uniprot summary :

LRP1: a receptor involved in endocytosis, phagocytosis of apoptotic cells, and neural signaling. Modulates cellular events including APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling and neurotransmission. Involved in the plasma clearance of chylomicron remnants and activated alpha 2-macroglobulin, as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Plays a fundamental role in cellular signaling pathways in the brain. Mediates neural NMDA gating via a complex of LRP1, PSD-95 and NMDAR. A type I membrane protein. After cleavage, the intracellular domain (LRPICD) is detected both in the cytoplasm and in the nucleus. Most abundant in liver, brain and lung. Protein type: Receptor, misc.; Membrane protein, integral; Motility/polarity/chemotaxis; Cell surface. Chromosomal Location of Human Ortholog: 12q13.3. Cellular Component: focal adhesion; clathrin-coated vesicle; cell soma; lysosomal membrane; integral to plasma membrane; dendrite; cytoplasm; nucleolus; plasma membrane; coated pit; receptor complex; endosome. Molecular Function: protein binding; lipoprotein transporter activity; protease binding; protein complex binding; apolipoprotein binding; receptor activity; calcium ion binding. Biological Process: receptor-mediated endocytosis; cholesterol metabolic process; phototransduction, visible light; regulation of phospholipase A2 activity; negative regulation of Wnt receptor signaling pathway; lipoprotein metabolic process; negative regulation of smooth muscle cell migration; positive regulation of protein transport; positive regulation of lipid transport; cell proliferation; lipoprotein transport; regulation of actin cytoskeleton organization and biogenesis; protein kinase C activation; negative regulation of neuron apoptosis; regulation of cholesterol transport; retinoid metabolic process; apoptotic cell clearance; aging

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage