catalog number :
MBS034801
products type :
ELISA Kit
products full name :
Rat Brevican ELISA Kit
products short name :
[Brevican]
other names :
[brevican core protein isoform 1; Brevican core protein; brevican core protein; chondroitin sulfate proteoglycan 7; chondroitin sulfate proteoglycan BEHAB; brain-enriched hyaluronan-binding protein; brevican; Brain-enriched hyaluronan-binding protein; BEHAB; Chondroitin sulfate proteoglycan 7]
products gene name :
[BCAN]
other gene names :
[BCAN; BCAN; BEHAB; CSPG7; BEHAB; CSPG7; BEHAB]
uniprot entry name :
PGCB_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of BCAN (hereafter termed this analyte) in undiluted original Rat serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_068767.3
ncbi gb acc num :
NM_021948.4
ncbi mol weight :
99,118 Da
ncbi pathways :
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway (645305); CS/DS Degradation Pathway (645311); Chondroitin Sulfate Biosynthesis Pathway (645309); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Degradation Of The Extracellular Matrix Pathway (576263); Dermatan Sulfate Biosynthesis Pathway (645310); Disease Pathway (530764); ECM Proteoglycans Pathway (833812); Extracellular Matrix Organization Pathway (576262); Glycogen Storage Diseases Pathway (980468)
ncbi summary :
This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
uniprot summary :
BCAN: May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. Belongs to the aggrecan/versican proteoglycan family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Membrane protein, GPI anchor; Secreted. Chromosomal Location of Human Ortholog: 1q31. Cellular Component: proteinaceous extracellular matrix; lysosomal lumen; Golgi lumen; extracellular region. Molecular Function: extracellular matrix structural constituent; hyaluronic acid binding; carbohydrate binding. Biological Process: chondroitin sulfate metabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; chondroitin sulfate biosynthetic process; central nervous system development; glycosaminoglycan metabolic process; hippocampus development; chondroitin sulfate catabolic process; carbohydrate metabolic process; pathogenesis; cell adhesion; skeletal development; dermatan sulfate biosynthetic process
size4 :
10x96-Strip-Wells