Mouse Thymic Stromal Lymphopoietin ELISA Kit | MyBioSource MBS034398 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Thymic Stromal Lymphopoietin ELISA Kit

catalog :

MBS034398

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS034398

products type :

ELISA Kit

products full name :

Mouse Thymic Stromal Lymphopoietin ELISA Kit

products short name :

Thymic Stromal Lymphopoietin

other names :

thymic stromal lymphopoietin isoform 2; Thymic stromal lymphopoietin; thymic stromal lymphopoietin; thymic stromal lymphopoietin

products gene name :

TSLP

other gene names :

TSLP; TSLP

uniprot entry name :

TSLP_HUMAN

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between Mouse TSLP and analogues was observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Assay Type: Sandwich. Detection Range: 6.25 pg/ml - 200 pg/ml. Sensitivity: 1.0 pg/ml.

other info2 :

Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated TSLP concentrations in Mouse serum, plasma and other body fluids. Using Purified Mouse TSLP antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add TSLP and TSLP antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of TSLP in the samples is then determined by comparing the O.D. of the samples to the standard curve. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean x100]

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated TSLP concentrations in Mouse serum, plasma and other body fluids. Using Purified Mouse TSLP antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add TSLP and TSLP antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of TSLP in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

190886449

ncbi acc num :

NP_612561.2

ncbi gb acc num :

NM_138551.4

uniprot acc num :

Q969D9

ncbi mol weight :

18,141 Da

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); TSLP Signaling Pathway (672451)

ncbi summary :

This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

uniprot summary :

TSLP: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 5q22.1. Cellular Component: extracellular space. Molecular Function: cytokine activity

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage