product summary
Loading...
company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse Bone Sialoprotein ELISA Kit
catalog :
MBS034175
quantity :
96 Strip Wells
price :
600 USD
more info or order :
product information
catalog number :
MBS034175
products type :
ELISA Kit
products full name :
Mouse Bone Sialoprotein ELISA Kit
products short name :
Bone Sialoprotein
other names :
bone sialoprotein 2; Bone sialoprotein 2; bone sialoprotein 2; BSP II; bone sialoprotein II; cell-binding sialoprotein; integrin-binding sialoprotein; Bone sialoprotein II; BSP II; Cell-binding sialoprotein; Integrin-binding sialoprotein
products gene name :
BSP
other gene names :
IBSP; IBSP; BSP; BNSP; SP-II; BSP-II; BNSP; BSP II
uniprot entry name :
SIAL_HUMAN
reactivity :
Mouse
sequence length :
317
storage stability :
Store all reagents at 2-8 degree C
other info1 :
ELISA Type: Sandwich
ncbi gi num :
167466187
ncbi acc num :
NP_004958.2
ncbi gb acc num :
NM_004967.3
uniprot acc num :
P21815
ncbi mol weight :
35,148 Da
ncbi pathways :
ECM Proteoglycans Pathway 833812!!ECM-receptor Interaction Pathway 83068!!ECM-receptor Interaction Pathway 479!!Extracellular Matrix Organization Pathway 576262!!Focal Adhesion Pathway 198795!!Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!Integrin Cell Surface Interactions Pathway 106110!!Interleukin-11 Signaling Pathway 698753!!Osteoblast Signaling Pathway 198842
ncbi summary :
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment. Subcellular location: Secreted. Post-translational modification: N-glycosylated; glycans consist of sialylated and core-fucosylated bi-, tri- and tetraantennary chains. Ref.6O-glycosylated at eight sites; mucin-type glycans contain Gal, GlcNAc, GalNAc and terminal NeuAc. Ref.6Sulfated on either Tyr-313 or Tyr-314. Miscellaneous: It is possible that the segments of clustered carboxyl groups mediate the strong binding to hydroxyapatite.
size :
96 Strip Wells
price :
600 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!