Mouse Glomerular Basement Membrane Antibody ELISA Kit | MyBioSource MBS034149 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Glomerular Basement Membrane Antibody ELISA Kit

catalog :

MBS034149

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS034149

products type :

ELISA Kit

products full name :

Mouse Glomerular Basement Membrane Antibody ELISA Kit

products short name :

[Glomerular Basement Membrane Antibody]

other names :

[glutamate--cysteine ligase regulatory subunit; Glutamate--cysteine ligase regulatory subunit; glutamate--cysteine ligase regulatory subunit; GCS light chain; GSC light chain; gamma-ECS regulatory subunit; glutamate--cysteine ligase modifier subunit; glutamate-cysteine ligase regulatory protein; gamma-glutamylcysteine synthetase regulatory subunit; glutamate-cysteine ligase modifier subunit delta2 alternative splicing; glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD); glutamate-cysteine ligase, modifier subunit; GCS light chain; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Glutamate--cysteine ligase modifier subunit]

products gene name :

[GBM]

other gene names :

[GCLM; GCLM; GLCLR; GLCLR]

uniprot entry name :

GSH0_HUMAN

reactivity :

Mouse

sequence length :

274

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of Anti-GBM (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

4504011

ncbi acc num :

NP_002052.1

ncbi gb acc num :

NM_002061.2

uniprot acc num :

P48507

ncbi mol weight :

30,727 Da

ncbi pathways :

Biological Oxidations Pathway (105698); Glutathione Biosynthesis, Glutamate = Glutathione Pathway (413393); Glutathione Biosynthesis, Glutamate = Glutathione Pathway (468307); Glutathione Conjugation Pathway (105727); Glutathione Metabolism Pathway (82973); Glutathione Metabolism Pathway (198824); Glutathione Metabolism Pathway (343); Glutathione Synthesis And Recycling Pathway (105728); Keap1-Nrf2 Pathway (198777); Metabolism Pathway (477135)

ncbi summary :

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq, Jul 2008]

uniprot summary :

GCLM: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq, Jul 2008]. Protein type: Other Amino Acids Metabolism - glutathione. Chromosomal Location of Human Ortholog: 1p22.1. Cellular Component: glutamate-cysteine ligase complex; cytosol. Molecular Function: protein heterodimerization activity; glutamate-cysteine ligase activity; enzyme regulator activity; glutamate-cysteine ligase catalytic subunit binding. Biological Process: response to drug; response to nitrosative stress; glutamate metabolic process; apoptotic mitochondrial changes; cysteine metabolic process; sulfur amino acid metabolic process; xenobiotic metabolic process; glutathione biosynthetic process; negative regulation of neuron apoptosis; response to oxidative stress; regulation of mitochondrial depolarization; regulation of blood vessel size; positive regulation of glutamate-cysteine ligase activity. Disease: Myocardial Infarction, Susceptibility To

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage