product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Kynurenine ELISA Kit
catalog :
MBS033463
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
product information
catalog number :
MBS033463
products type :
ELISA Kit
products full name :
Human Kynurenine ELISA Kit
products short name :
Kynurenine
other names :
kynurenine--oxoglutarate transaminase 3 isoform 2; Kynurenine--oxoglutarate transaminase 3; kynurenine--oxoglutarate transaminase 3; RP11-82K18.3; kynurenine aminotransferase III; cysteine-S-conjugate beta-lyase 2; kynurenine--glyoxylate transaminase; kynurenine-oxoglutarate transaminase 3; kynurenine--oxoglutarate transaminase III; cysteine conjugate-beta lyase 2; Cysteine-S-conjugate beta-lyase 2 (EC:4.4.1.13); Kynurenine aminotransferase III; KATIII; Kynurenine--glyoxylate transaminase (EC:2.6.1.63); Kynurenine--oxoglutarate transaminase III
products gene name :
KYNURENINE
other gene names :
CCBL2; CCBL2; KAT3; KATIII; KAT3; KATIII
uniprot entry name :
KAT3_HUMAN
reactivity :
Human
sequence length :
420
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 125 nmol/L - 4000 nmol/L. Sensitivity: 10 nmol/L.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of KYN (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
56713256
ncbi acc num :
NP_001008662.1
ncbi gb acc num :
NM_001008662.2
uniprot acc num :
Q6YP21
ncbi mol weight :
51,400 Da
ncbi pathways :
Chemical Carcinogenesis Pathway (673221); Chemical Carcinogenesis Pathway (673237); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169); Selenocompound Metabolism Pathway (82969); Selenocompound Metabolism Pathway (338); Tryptophan Catabolism Pathway (106190); Tryptophan Metabolism Pathway (82964); Tryptophan Metabolism Pathway (332); Tryptophan Degradation XI (mammalian, Via Kynurenine) Pathway (139210)
ncbi summary :
This gene encodes an aminotransferase that transaminates kynurenine to form kynurenic acid. Kynurenic acid is a metabolite of tryptophan. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene. This gene shares 5' exon structure with the RNA binding motif protein, X-linked-like 1 locus on chromosome 1, but the coding sequences are non-overlapping. [provided by RefSeq, Jun 2009]
uniprot summary :
CCBL2: Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se- conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2- oxoglutarate as amino group acceptor (in vitro). Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 2.6.1.63; EC 4.4.1.13; Transferase; Lyase; EC 2.6.1.7. Chromosomal Location of Human Ortholog: 1p22.2. Cellular Component: mitochondrion. Molecular Function: cysteine-S-conjugate beta-lyase activity; protein homodimerization activity; kynurenine-glyoxylate transaminase activity; kynurenine-oxoglutarate transaminase activity; pyridoxal phosphate binding. Biological Process: amino acid metabolic process; biosynthetic process; tryptophan catabolic process; 2-oxoglutarate metabolic process
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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